Coexpression cluster: Cluster_2 (HCCA)

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:0006082 organic acid metabolic process 8.74% (16/183) 2.51 0.0 1e-06
GO:0019752 carboxylic acid metabolic process 8.74% (16/183) 2.51 0.0 1e-06
GO:0043436 oxoacid metabolic process 8.74% (16/183) 2.51 0.0 1e-06
GO:0016874 ligase activity 7.65% (14/183) 2.71 0.0 1e-06
GO:0016875 ligase activity, forming carbon-oxygen bonds 6.01% (11/183) 3.23 0.0 1e-06
GO:0043038 amino acid activation 6.01% (11/183) 3.23 0.0 1e-06
GO:0004812 aminoacyl-tRNA ligase activity 6.01% (11/183) 3.23 0.0 1e-06
GO:0043039 tRNA aminoacylation 6.01% (11/183) 3.23 0.0 1e-06
GO:0006418 tRNA aminoacylation for protein translation 6.01% (11/183) 3.37 0.0 1e-06
GO:0006520 cellular amino acid metabolic process 7.65% (14/183) 2.53 0.0 4e-06
GO:0030554 adenyl nucleotide binding 18.03% (33/183) 1.39 0.0 8e-06
GO:0032559 adenyl ribonucleotide binding 18.03% (33/183) 1.39 0.0 8e-06
GO:0005524 ATP binding 18.03% (33/183) 1.4 0.0 8e-06
GO:0003674 molecular_function 62.84% (115/183) 0.5 0.0 1e-05
GO:0003824 catalytic activity 36.61% (67/183) 0.81 0.0 1.6e-05
GO:0140101 catalytic activity, acting on a tRNA 6.01% (11/183) 2.72 0.0 1.6e-05
GO:0008144 drug binding 18.03% (33/183) 1.31 1e-06 2.1e-05
GO:0044281 small molecule metabolic process 10.38% (19/183) 1.86 1e-06 2.4e-05
GO:0032553 ribonucleotide binding 19.13% (35/183) 1.2 2e-06 5.3e-05
GO:0097367 carbohydrate derivative binding 19.13% (35/183) 1.19 2e-06 5.4e-05
GO:0035639 purine ribonucleoside triphosphate binding 18.58% (34/183) 1.19 3e-06 7.9e-05
GO:0032555 purine ribonucleotide binding 18.58% (34/183) 1.19 3e-06 8e-05
GO:0017076 purine nucleotide binding 18.58% (34/183) 1.18 4e-06 8.9e-05
GO:0043168 anion binding 20.22% (37/183) 1.09 6e-06 0.000131
GO:0006399 tRNA metabolic process 6.01% (11/183) 2.34 8e-06 0.000162
GO:1901265 nucleoside phosphate binding 19.13% (35/183) 1.08 1.2e-05 0.000236
GO:0000166 nucleotide binding 19.13% (35/183) 1.08 1.2e-05 0.000236
GO:0036094 small molecule binding 19.67% (36/183) 1.03 1.9e-05 0.000359
GO:0051020 GTPase binding 3.83% (7/183) 2.87 3.1e-05 0.000575
GO:0005488 binding 39.34% (72/183) 0.6 3.5e-05 0.000616
GO:0140299 small molecule sensor activity 1.64% (3/183) 4.81 4.4e-05 0.000698
GO:0004673 protein histidine kinase activity 1.64% (3/183) 4.81 4.4e-05 0.000698
GO:0000155 phosphorelay sensor kinase activity 1.64% (3/183) 4.81 4.4e-05 0.000698
GO:0016775 phosphotransferase activity, nitrogenous group as acceptor 1.64% (3/183) 4.81 4.4e-05 0.000698
GO:0034660 ncRNA metabolic process 6.01% (11/183) 1.99 8.3e-05 0.001268
GO:0140098 catalytic activity, acting on RNA 6.01% (11/183) 1.97 9.3e-05 0.001388
GO:0043167 ion binding 22.95% (42/183) 0.8 0.000159 0.0023
GO:0043087 regulation of GTPase activity 1.64% (3/183) 4.4 0.000172 0.002432
GO:0019899 enzyme binding 3.83% (7/183) 2.45 0.000223 0.003066
GO:0017016 Ras GTPase binding 2.19% (4/183) 3.35 0.00042 0.005488
GO:0031267 small GTPase binding 2.19% (4/183) 3.35 0.00042 0.005488
GO:0046907 intracellular transport 4.92% (9/183) 1.83 0.000828 0.010323
GO:0000160 phosphorelay signal transduction system 1.64% (3/183) 3.81 0.000817 0.010433
GO:0051649 establishment of localization in cell 4.92% (9/183) 1.81 0.000918 0.011182
GO:0051345 positive regulation of hydrolase activity 1.09% (2/183) 4.81 0.001258 0.014658
GO:0043547 positive regulation of GTPase activity 1.09% (2/183) 4.81 0.001258 0.014658
GO:0051056 regulation of small GTPase mediated signal transduction 1.64% (3/183) 3.59 0.001393 0.014935
GO:0098797 plasma membrane protein complex 1.64% (3/183) 3.59 0.001393 0.014935
GO:0097159 organic cyclic compound binding 24.59% (45/183) 0.62 0.00139 0.015526
GO:1901363 heterocyclic compound binding 24.59% (45/183) 0.62 0.00139 0.015526
GO:0005515 protein binding 14.21% (26/183) 0.88 0.001562 0.016417
GO:0015002 heme-copper terminal oxidase activity 1.64% (3/183) 3.4 0.002171 0.021549
GO:0008536 Ran GTPase binding 1.64% (3/183) 3.4 0.002171 0.021549
GO:1902531 regulation of intracellular signal transduction 1.64% (3/183) 3.4 0.002171 0.021549
GO:0051641 cellular localization 4.92% (9/183) 1.63 0.002329 0.0227
GO:0098796 membrane protein complex 4.37% (8/183) 1.75 0.002375 0.022728
GO:0008150 biological_process 42.62% (78/183) 0.39 0.002417 0.022733
GO:0015078 proton transmembrane transporter activity 2.73% (5/183) 2.23 0.00372 0.032691
GO:0044093 positive regulation of molecular function 1.09% (2/183) 4.23 0.003685 0.032923
GO:0043085 positive regulation of catalytic activity 1.09% (2/183) 4.23 0.003685 0.032923
GO:0006493 protein O-linked glycosylation 1.09% (2/183) 4.23 0.003685 0.032923
GO:0023051 regulation of signaling 1.64% (3/183) 3.08 0.004413 0.035842
GO:0010646 regulation of cell communication 1.64% (3/183) 3.08 0.004413 0.035842
GO:0051336 regulation of hydrolase activity 1.64% (3/183) 3.08 0.004413 0.035842
GO:0048583 regulation of response to stimulus 1.64% (3/183) 3.08 0.004413 0.035842
GO:0009966 regulation of signal transduction 1.64% (3/183) 3.08 0.004413 0.035842
GO:0016070 RNA metabolic process 8.74% (16/183) 1.03 0.00479 0.038319
GO:0015077 monovalent inorganic cation transmembrane transporter activity 2.73% (5/183) 2.09 0.005685 0.044813
GO:1901564 organonitrogen compound metabolic process 16.39% (30/183) 0.68 0.005987 0.046511
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
Saccharomyces cerevisiae HCCA Cluster_1 0.037 OF Compare
Saccharomyces cerevisiae HCCA Cluster_7 0.051 OF Compare
Saccharomyces cerevisiae HCCA Cluster_8 0.093 OF Compare
Saccharomyces cerevisiae HCCA Cluster_12 0.124 OF Compare
Saccharomyces cerevisiae HCCA Cluster_23 0.024 OF Compare
Saccharomyces cerevisiae HCCA Cluster_39 0.021 OF Compare
Saccharomyces cerevisiae HCCA Cluster_41 0.018 OF Compare
Saccharomyces cerevisiae HCCA Cluster_48 0.032 OF Compare
Saccharomyces cerevisiae HCCA Cluster_54 0.058 OF Compare
Saccharomyces cerevisiae HCCA Cluster_55 0.023 OF Compare
Saccharomyces cerevisiae HCCA Cluster_56 0.031 OF Compare
Aspergillus flavus HCCA Cluster_4 0.023 OF Compare
Aspergillus fumigatus HCCA Cluster_1 0.02 OF Compare
Aspergillus fumigatus HCCA Cluster_7 0.028 OF Compare
Aspergillus fumigatus HCCA Cluster_16 0.057 OF Compare
Aspergillus fumigatus HCCA Cluster_24 0.114 OF Compare
Aspergillus fumigatus HCCA Cluster_41 0.02 OF Compare
Aspergillus fumigatus HCCA Cluster_54 0.035 OF Compare
Aspergillus fumigatus HCCA Cluster_75 0.04 OF Compare
Aspergillus nidulans HCCA Cluster_15 0.021 OF Compare
Aspergillus nidulans HCCA Cluster_27 0.026 OF Compare
Aspergillus nidulans HCCA Cluster_38 0.112 OF Compare
Aspergillus nidulans HCCA Cluster_46 0.092 OF Compare
Aspergillus nidulans HCCA Cluster_66 0.029 OF Compare
Aspergillus nidulans HCCA Cluster_71 0.02 OF Compare
Aspergillus nidulans HCCA Cluster_81 0.019 OF Compare
Aspergillus nidulans HCCA Cluster_96 0.018 OF Compare
Aspergillus nidulans HCCA Cluster_97 0.021 OF Compare
Aspergillus niger HCCA Cluster_20 0.04 OF Compare
Aspergillus niger HCCA Cluster_36 0.027 OF Compare
Aspergillus niger HCCA Cluster_42 0.049 OF Compare
Aspergillus niger HCCA Cluster_53 0.028 OF Compare
Aspergillus niger HCCA Cluster_65 0.057 OF Compare
Aspergillus niger HCCA Cluster_66 0.022 OF Compare
Aspergillus niger HCCA Cluster_74 0.023 OF Compare
Aspergillus niger HCCA Cluster_84 0.031 OF Compare
Aspergillus niger HCCA Cluster_90 0.018 OF Compare
Aspergillus niger HCCA Cluster_128 0.02 OF Compare
Candida albicans HCCA Cluster_15 0.098 OF Compare
Candida albicans HCCA Cluster_19 0.024 OF Compare
Candida albicans HCCA Cluster_25 0.115 OF Compare
Candida albicans HCCA Cluster_38 0.026 OF Compare
Candida albicans HCCA Cluster_42 0.027 OF Compare
Candida albicans HCCA Cluster_49 0.022 OF Compare
Candida albicans HCCA Cluster_55 0.065 OF Compare
Coprinopsis cinerea HCCA Cluster_43 0.025 OF Compare
Coprinopsis cinerea HCCA Cluster_54 0.019 OF Compare
Coprinopsis cinerea HCCA Cluster_61 0.026 OF Compare
Coprinopsis cinerea HCCA Cluster_65 0.06 OF Compare
Coprinopsis cinerea HCCA Cluster_96 0.047 OF Compare
Coprinopsis cinerea HCCA Cluster_99 0.027 OF Compare
Coprinopsis cinerea HCCA Cluster_120 0.026 OF Compare
Coprinopsis cinerea HCCA Cluster_128 0.029 OF Compare
Cryptococcus neoformans HCCA Cluster_3 0.025 OF Compare
Cryptococcus neoformans HCCA Cluster_13 0.04 OF Compare
Cryptococcus neoformans HCCA Cluster_18 0.034 OF Compare
Cryptococcus neoformans HCCA Cluster_27 0.02 OF Compare
Cryptococcus neoformans HCCA Cluster_31 0.066 OF Compare
Cryptococcus neoformans HCCA Cluster_39 0.018 OF Compare
Cryptococcus neoformans HCCA Cluster_55 0.052 OF Compare
Cryptococcus neoformans HCCA Cluster_56 0.031 OF Compare
Cryptococcus neoformans HCCA Cluster_65 0.038 OF Compare
Cryptococcus neoformans HCCA Cluster_72 0.019 OF Compare
Cryptococcus neoformans HCCA Cluster_83 0.032 OF Compare
Dichomitus squalens HCCA Cluster_9 0.04 OF Compare
Dichomitus squalens HCCA Cluster_24 0.019 OF Compare
Dichomitus squalens HCCA Cluster_40 0.027 OF Compare
Dichomitus squalens HCCA Cluster_60 0.017 OF Compare
Dichomitus squalens HCCA Cluster_62 0.03 OF Compare
Fusarium graminearum HCCA Cluster_10 0.019 OF Compare
Fusarium graminearum HCCA Cluster_21 0.019 OF Compare
Fusarium graminearum HCCA Cluster_37 0.046 OF Compare
Fusarium graminearum HCCA Cluster_48 0.042 OF Compare
Fusarium graminearum HCCA Cluster_59 0.05 OF Compare
Fusarium graminearum HCCA Cluster_62 0.026 OF Compare
Fusarium graminearum HCCA Cluster_66 0.035 OF Compare
Fusarium graminearum HCCA Cluster_84 0.029 OF Compare
Fusarium graminearum HCCA Cluster_119 0.04 OF Compare
Komagataella phaffii HCCA Cluster_1 0.08 OF Compare
Komagataella phaffii HCCA Cluster_10 0.035 OF Compare
Komagataella phaffii HCCA Cluster_20 0.018 OF Compare
Komagataella phaffii HCCA Cluster_25 0.051 OF Compare
Komagataella phaffii HCCA Cluster_35 0.043 OF Compare
Komagataella phaffii HCCA Cluster_36 0.072 OF Compare
Komagataella phaffii HCCA Cluster_47 0.04 OF Compare
Neurospora crassa HCCA Cluster_18 0.068 OF Compare
Neurospora crassa HCCA Cluster_22 0.037 OF Compare
Neurospora crassa HCCA Cluster_28 0.033 OF Compare
Neurospora crassa HCCA Cluster_32 0.023 OF Compare
Neurospora crassa HCCA Cluster_45 0.062 OF Compare
Neurospora crassa HCCA Cluster_60 0.027 OF Compare
Neurospora crassa HCCA Cluster_61 0.037 OF Compare
Neurospora crassa HCCA Cluster_63 0.021 OF Compare
Neurospora crassa HCCA Cluster_80 0.018 OF Compare
Neurospora crassa HCCA Cluster_85 0.027 OF Compare
Neurospora crassa HCCA Cluster_89 0.027 OF Compare
Neurospora crassa HCCA Cluster_95 0.018 OF Compare
Postia placenta HCCA Cluster_3 0.037 OF Compare
Postia placenta HCCA Cluster_33 0.017 OF Compare
Postia placenta HCCA Cluster_51 0.022 OF Compare
Postia placenta HCCA Cluster_66 0.02 OF Compare
Puccinia striiformis HCCA Cluster_15 0.018 OF Compare
Puccinia striiformis HCCA Cluster_26 0.031 OF Compare
Puccinia striiformis HCCA Cluster_31 0.058 OF Compare
Puccinia striiformis HCCA Cluster_54 0.032 OF Compare
Puccinia striiformis HCCA Cluster_78 0.024 OF Compare
Puccinia striiformis HCCA Cluster_94 0.037 OF Compare
Puccinia striiformis HCCA Cluster_98 0.024 OF Compare
Puccinia striiformis HCCA Cluster_99 0.018 OF Compare
Pyricularia oryzae HCCA Cluster_1 0.018 OF Compare
Pyricularia oryzae HCCA Cluster_23 0.042 OF Compare
Pyricularia oryzae HCCA Cluster_53 0.032 OF Compare
Pyricularia oryzae HCCA Cluster_57 0.023 OF Compare
Pyricularia oryzae HCCA Cluster_60 0.018 OF Compare
Pyricularia oryzae HCCA Cluster_73 0.091 OF Compare
Pyricularia oryzae HCCA Cluster_88 0.022 OF Compare
Pyricularia oryzae HCCA Cluster_98 0.02 OF Compare
Pyricularia oryzae HCCA Cluster_110 0.025 OF Compare
Pyricularia oryzae HCCA Cluster_119 0.079 OF Compare
Yarrowia lipolytica HCCA Cluster_1 0.07 OF Compare
Yarrowia lipolytica HCCA Cluster_13 0.029 OF Compare
Yarrowia lipolytica HCCA Cluster_18 0.07 OF Compare
Yarrowia lipolytica HCCA Cluster_25 0.021 OF Compare
Yarrowia lipolytica HCCA Cluster_28 0.06 OF Compare
Yarrowia lipolytica HCCA Cluster_31 0.043 OF Compare
Yarrowia lipolytica HCCA Cluster_36 0.021 OF Compare
Yarrowia lipolytica HCCA Cluster_43 0.022 OF Compare
Yarrowia lipolytica HCCA Cluster_53 0.023 OF Compare
Yarrowia lipolytica HCCA Cluster_62 0.023 OF Compare
Trichoderma reesei HCCA Cluster_2 0.019 OF Compare
Trichoderma reesei HCCA Cluster_3 0.046 OF Compare
Trichoderma reesei HCCA Cluster_16 0.027 OF Compare
Trichoderma reesei HCCA Cluster_20 0.021 OF Compare
Trichoderma reesei HCCA Cluster_38 0.11 OF Compare
Trichoderma reesei HCCA Cluster_54 0.047 OF Compare
Trichoderma reesei HCCA Cluster_70 0.04 OF Compare
Trichoderma reesei HCCA Cluster_79 0.018 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_22 0.027 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_26 0.039 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_58 0.019 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_59 0.068 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_79 0.018 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_86 0.038 OF Compare
Sequences (183) (download table)

InterPro Domains

GO Terms

Family Terms