GO:0000155: phosphorelay sensor kinase activity (Molecular function)

"Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response." [GOC:bf, GOC:mcc, PMID:10966457, PMID:20223701, PMID:9191038]


There are 142 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_12 Saccharomyces cerevisiae 1.67 % 0.009091 0.049862
Cluster_14 Aspergillus nidulans 2.27 % 4.8e-05 0.002884
Cluster_6 Dichomitus squalens 2.33 % 0.000835 0.028626
Cluster_63 Fusarium graminearum 4.08 % 0.001174 0.010501
Cluster_21 Komagataella phaffii 1.75 % 0.000502 0.010695
Cluster_9 Neurospora crassa 1.9 % 0.000612 0.013925
Cluster_78 Neurospora crassa 2.94 % 0.000169 0.010211
Cluster_66 Yarrowia lipolytica 4.55 % 0.000271 0.012588
Cluster_2 Schizosaccharomyces pombe 1.64 % 4.4e-05 0.000698
Cluster_59 Trichoderma reesei 6.45 % 0.0 1.1e-05
Cluster_86 Sclerotinia sclerotiorum 1.37 % 0.001428 0.005713
Sequences (142) (download table)

InterPro Domains

GO Terms

Family Terms