GO:0016874: ligase activity (Molecular function)

"Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [EC:6, GOC:mah]


There are 1151 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_7 Saccharomyces cerevisiae 4.62 % 1.2e-05 0.000173
Cluster_54 Saccharomyces cerevisiae 8.51 % 0.000989 0.004568
Cluster_8 Saccharomyces cerevisiae 11.11 % 0.0 1e-06
Cluster_49 Saccharomyces cerevisiae 24.53 % 0.0 0.0
Cluster_7 Aspergillus fumigatus 4.82 % 0.0 3e-06
Cluster_16 Aspergillus fumigatus 9.38 % 0.0 0.0
Cluster_66 Aspergillus fumigatus 3.7 % 0.017979 0.035494
Cluster_96 Aspergillus nidulans 7.27 % 0.000377 0.004504
Cluster_46 Aspergillus nidulans 18.18 % 0.0 0.0
Cluster_105 Aspergillus nidulans 8.62 % 2.9e-05 0.000753
Cluster_66 Aspergillus nidulans 5.81 % 0.000195 0.002332
Cluster_2 Aspergillus niger 5.07 % 5e-06 3e-05
Cluster_42 Aspergillus niger 12.28 % 0.0 0.0
Cluster_120 Aspergillus niger 4.92 % 0.003263 0.018592
Cluster_15 Candida albicans 13.84 % 0.0 0.0
Cluster_39 Candida albicans 7.22 % 2.7e-05 0.00018
Cluster_99 Coprinopsis cinerea 4.35 % 0.000718 0.003795
Cluster_120 Coprinopsis cinerea 14.06 % 0.0 0.0
Cluster_16 Cryptococcus neoformans 5.88 % 0.007194 0.033066
Cluster_55 Cryptococcus neoformans 10.14 % 1e-06 1.4e-05
Cluster_13 Cryptococcus neoformans 7.62 % 0.0 0.0
Cluster_58 Dichomitus squalens 4.76 % 0.000248 0.007652
Cluster_9 Dichomitus squalens 7.38 % 0.0 0.0
Cluster_40 Fusarium graminearum 2.31 % 0.014284 0.036457
Cluster_112 Fusarium graminearum 7.41 % 0.000203 0.000917
Cluster_37 Fusarium graminearum 12.0 % 0.0 0.0
Cluster_77 Fusarium graminearum 4.05 % 0.007472 0.02326
Cluster_125 Fusarium graminearum 4.84 % 0.004565 0.021536
Cluster_1 Komagataella phaffii 11.39 % 0.0 0.0
Cluster_51 Neurospora crassa 5.19 % 0.002073 0.022556
Cluster_8 Neurospora crassa 6.43 % 0.0 1e-06
Cluster_45 Neurospora crassa 12.04 % 0.0 0.0
Cluster_129 Postia placenta 100.0 % 7e-06 1.3e-05
Cluster_156 Postia placenta 50.0 % 0.005278 0.0203
Cluster_66 Postia placenta 2.41 % 0.01999 0.045766
Cluster_77 Puccinia striiformis 8.57 % 1e-06 0.000328
Cluster_21 Puccinia striiformis 2.74 % 0.006008 0.019058
Cluster_26 Puccinia striiformis 5.3 % 4e-06 5.2e-05
Cluster_78 Puccinia striiformis 6.59 % 6e-06 9.8e-05
Cluster_31 Puccinia striiformis 3.21 % 0.001068 0.005325
Cluster_55 Puccinia striiformis 3.77 % 0.028529 0.047615
Cluster_90 Pyricularia oryzae 3.68 % 0.000633 0.003174
Cluster_60 Pyricularia oryzae 3.7 % 0.002214 0.029548
Cluster_88 Pyricularia oryzae 6.45 % 0.000274 0.002909
Cluster_85 Pyricularia oryzae 8.33 % 0.000101 0.001439
Cluster_73 Pyricularia oryzae 7.49 % 0.0 0.0
Cluster_31 Yarrowia lipolytica 7.59 % 0.0 1e-06
Cluster_25 Yarrowia lipolytica 12.16 % 0.0 1e-06
Cluster_18 Yarrowia lipolytica 19.3 % 0.0 0.0
Cluster_2 Schizosaccharomyces pombe 7.65 % 0.0 1e-06
Cluster_85 Trichoderma reesei 5.45 % 0.006679 0.049792
Cluster_70 Trichoderma reesei 8.33 % 5.9e-05 0.000443
Cluster_37 Trichoderma reesei 5.68 % 0.000364 0.008812
Cluster_3 Trichoderma reesei 6.2 % 3e-06 6.3e-05
Cluster_64 Trichoderma reesei 9.43 % 3.2e-05 0.00751
Cluster_12 Trichoderma reesei 3.14 % 0.002139 0.021288
Cluster_32 Sclerotinia sclerotiorum 5.63 % 0.00031 0.001118
Cluster_5 Sclerotinia sclerotiorum 3.37 % 0.000156 0.00122
Cluster_59 Sclerotinia sclerotiorum 8.92 % 0.0 0.0
Sequences (1151) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms