Coexpression cluster: Cluster_18 (HCCA)

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:0006520 cellular amino acid metabolic process 33.33% (19/57) 5.0 0.0 0.0
GO:0019752 carboxylic acid metabolic process 35.09% (20/57) 4.64 0.0 0.0
GO:0006082 organic acid metabolic process 35.09% (20/57) 4.64 0.0 0.0
GO:0043436 oxoacid metabolic process 35.09% (20/57) 4.64 0.0 0.0
GO:0044281 small molecule metabolic process 38.6% (22/57) 4.0 0.0 0.0
GO:0016053 organic acid biosynthetic process 17.54% (10/57) 5.62 0.0 0.0
GO:0046394 carboxylic acid biosynthetic process 17.54% (10/57) 5.62 0.0 0.0
GO:0008652 cellular amino acid biosynthetic process 15.79% (9/57) 5.82 0.0 0.0
GO:0009072 aromatic amino acid family metabolic process 12.28% (7/57) 6.17 0.0 0.0
GO:0044283 small molecule biosynthetic process 17.54% (10/57) 4.79 0.0 0.0
GO:0016874 ligase activity 19.3% (11/57) 4.37 0.0 0.0
GO:1901607 alpha-amino acid biosynthetic process 12.28% (7/57) 5.82 0.0 0.0
GO:1901605 alpha-amino acid metabolic process 14.04% (8/57) 5.18 0.0 0.0
GO:1901564 organonitrogen compound metabolic process 38.6% (22/57) 2.38 0.0 0.0
GO:0009073 aromatic amino acid family biosynthetic process 10.53% (6/57) 6.24 0.0 0.0
GO:0006418 tRNA aminoacylation for protein translation 14.04% (8/57) 4.96 0.0 0.0
GO:0043039 tRNA aminoacylation 14.04% (8/57) 4.78 0.0 0.0
GO:0043038 amino acid activation 14.04% (8/57) 4.78 0.0 0.0
GO:0016875 ligase activity, forming carbon-oxygen bonds 14.04% (8/57) 4.78 0.0 0.0
GO:0004812 aminoacyl-tRNA ligase activity 14.04% (8/57) 4.78 0.0 0.0
GO:0006725 cellular aromatic compound metabolic process 31.58% (18/57) 2.56 0.0 0.0
GO:1901360 organic cyclic compound metabolic process 31.58% (18/57) 2.52 0.0 0.0
GO:0140101 catalytic activity, acting on a tRNA 14.04% (8/57) 4.3 0.0 0.0
GO:0008152 metabolic process 52.63% (30/57) 1.51 0.0 0.0
GO:0003824 catalytic activity 54.39% (31/57) 1.44 0.0 0.0
GO:1901566 organonitrogen compound biosynthetic process 21.05% (12/57) 3.07 0.0 0.0
GO:0052803 imidazole-containing compound metabolic process 7.02% (4/57) 6.5 0.0 0.0
GO:0006547 histidine metabolic process 7.02% (4/57) 6.5 0.0 0.0
GO:0000105 histidine biosynthetic process 7.02% (4/57) 6.5 0.0 0.0
GO:0046483 heterocycle metabolic process 28.07% (16/57) 2.39 0.0 0.0
GO:0006399 tRNA metabolic process 14.04% (8/57) 3.94 0.0 0.0
GO:0006807 nitrogen compound metabolic process 38.6% (22/57) 1.77 0.0 1e-06
GO:0034641 cellular nitrogen compound metabolic process 29.82% (17/57) 2.09 0.0 1e-06
GO:0034660 ncRNA metabolic process 14.04% (8/57) 3.57 0.0 2e-06
GO:0009058 biosynthetic process 26.32% (15/57) 2.25 0.0 2e-06
GO:0036094 small molecule binding 31.58% (18/57) 1.94 0.0 2e-06
GO:0016829 lyase activity 10.53% (6/57) 4.36 0.0 2e-06
GO:0044237 cellular metabolic process 38.6% (22/57) 1.65 0.0 2e-06
GO:0016835 carbon-oxygen lyase activity 7.02% (4/57) 5.5 1e-06 6e-06
GO:0140098 catalytic activity, acting on RNA 14.04% (8/57) 3.3 1e-06 7e-06
GO:0019438 aromatic compound biosynthetic process 15.79% (9/57) 2.93 2e-06 1.2e-05
GO:0071704 organic substance metabolic process 38.6% (22/57) 1.47 3e-06 1.7e-05
GO:1901362 organic cyclic compound biosynthetic process 15.79% (9/57) 2.84 3e-06 1.8e-05
GO:0044238 primary metabolic process 36.84% (21/57) 1.51 4e-06 2e-05
GO:0043168 anion binding 28.07% (16/57) 1.81 6e-06 2.9e-05
GO:0044249 cellular biosynthetic process 21.05% (12/57) 2.14 1.2e-05 5.9e-05
GO:0008144 drug binding 22.81% (13/57) 2.0 1.3e-05 6.4e-05
GO:1901576 organic substance biosynthetic process 21.05% (12/57) 2.08 1.8e-05 8.4e-05
GO:0043167 ion binding 31.58% (18/57) 1.45 4.4e-05 0.000203
GO:0016836 hydro-lyase activity 5.26% (3/57) 5.24 5.3e-05 0.000242
GO:0000166 nucleotide binding 24.56% (14/57) 1.68 7.3e-05 0.000318
GO:1901265 nucleoside phosphate binding 24.56% (14/57) 1.68 7.3e-05 0.000318
GO:0008150 biological_process 54.39% (31/57) 0.87 8.3e-05 0.000359
GO:0005524 ATP binding 19.3% (11/57) 1.88 0.00015 0.000634
GO:0018130 heterocycle biosynthetic process 12.28% (7/57) 2.56 0.000159 0.000648
GO:0032559 adenyl ribonucleotide binding 19.3% (11/57) 1.87 0.000158 0.000656
GO:0030554 adenyl nucleotide binding 19.3% (11/57) 1.86 0.000167 0.000667
GO:0016879 ligase activity, forming carbon-nitrogen bonds 5.26% (3/57) 4.6 0.000223 0.000875
GO:0050662 coenzyme binding 10.53% (6/57) 2.72 0.000269 0.001041
GO:0006139 nucleobase-containing compound metabolic process 17.54% (10/57) 1.83 0.000413 0.001568
GO:0003674 molecular_function 63.16% (36/57) 0.64 0.000479 0.001789
GO:0016070 RNA metabolic process 14.04% (8/57) 2.09 0.000493 0.001814
GO:0009987 cellular process 40.35% (23/57) 0.93 0.000773 0.002796
GO:0035639 purine ribonucleoside triphosphate binding 19.3% (11/57) 1.58 0.00089 0.003172
GO:0032555 purine ribonucleotide binding 19.3% (11/57) 1.57 0.000926 0.00325
GO:1901363 heterocyclic compound binding 29.82% (17/57) 1.14 0.000981 0.003337
GO:0097159 organic cyclic compound binding 29.82% (17/57) 1.14 0.000981 0.003337
GO:0017076 purine nucleotide binding 19.3% (11/57) 1.56 0.001002 0.00336
GO:0032553 ribonucleotide binding 19.3% (11/57) 1.53 0.001192 0.003937
GO:0097367 carbohydrate derivative binding 19.3% (11/57) 1.52 0.001237 0.00403
GO:0048037 cofactor binding 10.53% (6/57) 2.22 0.001705 0.005475
GO:0090304 nucleic acid metabolic process 14.04% (8/57) 1.73 0.002532 0.008019
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 5.26% (3/57) 3.36 0.002961 0.009249
GO:0019842 vitamin binding 5.26% (3/57) 3.32 0.003227 0.009944
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 5.26% (3/57) 3.28 0.003508 0.010665
GO:0003879 ATP phosphoribosyltransferase activity 1.75% (1/57) 6.82 0.00884 0.019014
GO:0004834 tryptophan synthase activity 1.75% (1/57) 6.82 0.00884 0.019014
GO:0004150 dihydroneopterin aldolase activity 1.75% (1/57) 6.82 0.00884 0.019014
GO:0046040 IMP metabolic process 1.75% (1/57) 6.82 0.00884 0.019014
GO:0003848 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity 1.75% (1/57) 6.82 0.00884 0.019014
GO:0004358 glutamate N-acetyltransferase activity 1.75% (1/57) 6.82 0.00884 0.019014
GO:0006525 arginine metabolic process 1.75% (1/57) 6.82 0.00884 0.019014
GO:0006526 arginine biosynthetic process 1.75% (1/57) 6.82 0.00884 0.019014
GO:0004399 histidinol dehydrogenase activity 1.75% (1/57) 6.82 0.00884 0.019014
GO:0004107 chorismate synthase activity 1.75% (1/57) 6.82 0.00884 0.019014
GO:0004814 arginine-tRNA ligase activity 1.75% (1/57) 6.82 0.00884 0.019014
GO:0006188 IMP biosynthetic process 1.75% (1/57) 6.82 0.00884 0.019014
GO:0004425 indole-3-glycerol-phosphate synthase activity 1.75% (1/57) 6.82 0.00884 0.019014
GO:0006420 arginyl-tRNA aminoacylation 1.75% (1/57) 6.82 0.00884 0.019014
GO:0016838 carbon-oxygen lyase activity, acting on phosphates 1.75% (1/57) 6.82 0.00884 0.019014
GO:1902223 erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process 1.75% (1/57) 6.82 0.00884 0.019014
GO:0009113 purine nucleobase biosynthetic process 1.75% (1/57) 6.82 0.00884 0.019014
GO:0009112 nucleobase metabolic process 1.75% (1/57) 6.82 0.00884 0.019014
GO:0006144 purine nucleobase metabolic process 1.75% (1/57) 6.82 0.00884 0.019014
GO:0004637 phosphoribosylamine-glycine ligase activity 1.75% (1/57) 6.82 0.00884 0.019014
GO:0003855 3-dehydroquinate dehydratase activity 1.75% (1/57) 6.82 0.00884 0.019014
GO:0004635 phosphoribosyl-AMP cyclohydrolase activity 1.75% (1/57) 6.82 0.00884 0.019014
GO:0004764 shikimate 3-dehydrogenase (NADP+) activity 1.75% (1/57) 6.82 0.00884 0.019014
GO:0006189 'de novo' IMP biosynthetic process 1.75% (1/57) 6.82 0.00884 0.019014
GO:1902221 erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process 1.75% (1/57) 6.82 0.00884 0.019014
GO:0009094 L-phenylalanine biosynthetic process 1.75% (1/57) 6.82 0.00884 0.019014
GO:0006558 L-phenylalanine metabolic process 1.75% (1/57) 6.82 0.00884 0.019014
GO:0046112 nucleobase biosynthetic process 1.75% (1/57) 6.82 0.00884 0.019014
GO:0004664 prephenate dehydratase activity 1.75% (1/57) 6.82 0.00884 0.019014
GO:0016491 oxidoreductase activity 12.28% (7/57) 1.56 0.009016 0.019211
GO:0016830 carbon-carbon lyase activity 3.51% (2/57) 4.01 0.006527 0.01958
GO:0055114 oxidation-reduction process 12.28% (7/57) 1.63 0.006794 0.020116
GO:0000287 magnesium ion binding 3.51% (2/57) 3.65 0.010728 0.022648
GO:0072522 purine-containing compound biosynthetic process 3.51% (2/57) 3.57 0.011922 0.024939
GO:0016832 aldehyde-lyase activity 1.75% (1/57) 5.82 0.017603 0.030177
GO:0016743 carboxyl- or carbamoyltransferase activity 1.75% (1/57) 5.82 0.017603 0.030177
GO:0009123 nucleoside monophosphate metabolic process 1.75% (1/57) 5.82 0.017603 0.030177
GO:0016597 amino acid binding 1.75% (1/57) 5.82 0.017603 0.030177
GO:0009124 nucleoside monophosphate biosynthetic process 1.75% (1/57) 5.82 0.017603 0.030177
GO:0009095 aromatic amino acid family biosynthetic process, prephenate pathway 1.75% (1/57) 5.82 0.017603 0.030177
GO:0006760 folic acid-containing compound metabolic process 1.75% (1/57) 5.82 0.017603 0.030177
GO:0009168 purine ribonucleoside monophosphate biosynthetic process 1.75% (1/57) 5.82 0.017603 0.030177
GO:0009167 purine ribonucleoside monophosphate metabolic process 1.75% (1/57) 5.82 0.017603 0.030177
GO:0009396 folic acid-containing compound biosynthetic process 1.75% (1/57) 5.82 0.017603 0.030177
GO:0009161 ribonucleoside monophosphate metabolic process 1.75% (1/57) 5.82 0.017603 0.030177
GO:0009127 purine nucleoside monophosphate biosynthetic process 1.75% (1/57) 5.82 0.017603 0.030177
GO:0009126 purine nucleoside monophosphate metabolic process 1.75% (1/57) 5.82 0.017603 0.030177
GO:0019238 cyclohydrolase activity 1.75% (1/57) 5.82 0.017603 0.030177
GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity 1.75% (1/57) 5.82 0.017603 0.030177
GO:0004329 formate-tetrahydrofolate ligase activity 1.75% (1/57) 5.82 0.017603 0.030177
GO:0006528 asparagine metabolic process 1.75% (1/57) 5.82 0.017603 0.030177
GO:0006568 tryptophan metabolic process 1.75% (1/57) 5.82 0.017603 0.030177
GO:0009156 ribonucleoside monophosphate biosynthetic process 1.75% (1/57) 5.82 0.017603 0.030177
GO:0006586 indolalkylamine metabolic process 1.75% (1/57) 5.82 0.017603 0.030177
GO:0042430 indole-containing compound metabolic process 1.75% (1/57) 5.82 0.017603 0.030177
GO:0006529 asparagine biosynthetic process 1.75% (1/57) 5.82 0.017603 0.030177
GO:0072521 purine-containing compound metabolic process 3.51% (2/57) 3.18 0.020221 0.034406
GO:0005488 binding 35.09% (20/57) 0.67 0.016768 0.034441
GO:0016740 transferase activity 14.04% (8/57) 1.27 0.016659 0.034529
GO:0051287 NAD binding 3.51% (2/57) 3.07 0.023394 0.03951
GO:0042559 pteridine-containing compound biosynthetic process 1.75% (1/57) 5.24 0.02629 0.039961
GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity 1.75% (1/57) 5.24 0.02629 0.039961
GO:0004486 methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity 1.75% (1/57) 5.24 0.02629 0.039961
GO:0006576 cellular biogenic amine metabolic process 1.75% (1/57) 5.24 0.02629 0.039961
GO:0046148 pigment biosynthetic process 1.75% (1/57) 5.24 0.02629 0.039961
GO:0042558 pteridine-containing compound metabolic process 1.75% (1/57) 5.24 0.02629 0.039961
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1.75% (1/57) 5.24 0.02629 0.039961
GO:0044106 cellular amine metabolic process 1.75% (1/57) 5.24 0.02629 0.039961
GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1.75% (1/57) 5.24 0.02629 0.039961
GO:0009084 glutamine family amino acid biosynthetic process 1.75% (1/57) 5.24 0.02629 0.039961
GO:0031406 carboxylic acid binding 1.75% (1/57) 5.24 0.02629 0.039961
GO:0043177 organic acid binding 1.75% (1/57) 5.24 0.02629 0.039961
GO:0009067 aspartate family amino acid biosynthetic process 1.75% (1/57) 5.24 0.02629 0.039961
GO:0030170 pyridoxal phosphate binding 3.51% (2/57) 3.01 0.025052 0.041693
GO:0070279 vitamin B6 binding 3.51% (2/57) 3.01 0.025052 0.041693
GO:0005737 cytoplasm 3.51% (2/57) 2.91 0.028508 0.043046
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
Saccharomyces cerevisiae HCCA Cluster_7 0.148 OF Compare
Saccharomyces cerevisiae HCCA Cluster_8 0.047 OF Compare
Saccharomyces cerevisiae HCCA Cluster_49 0.019 OF Compare
Saccharomyces cerevisiae HCCA Cluster_54 0.02 OF Compare
Saccharomyces cerevisiae HCCA Cluster_58 0.022 OF Compare
Aspergillus flavus HCCA Cluster_9 0.018 OF Compare
Aspergillus fumigatus HCCA Cluster_7 0.022 OF Compare
Aspergillus fumigatus HCCA Cluster_16 0.16 OF Compare
Aspergillus fumigatus HCCA Cluster_86 0.017 OF Compare
Aspergillus nidulans HCCA Cluster_27 0.068 OF Compare
Aspergillus nidulans HCCA Cluster_46 0.139 OF Compare
Aspergillus nidulans HCCA Cluster_62 0.023 OF Compare
Aspergillus nidulans HCCA Cluster_66 0.079 OF Compare
Aspergillus nidulans HCCA Cluster_105 0.018 OF Compare
Aspergillus niger HCCA Cluster_42 0.137 OF Compare
Aspergillus niger HCCA Cluster_53 0.13 OF Compare
Aspergillus niger HCCA Cluster_67 0.04 OF Compare
Candida albicans HCCA Cluster_3 0.028 OF Compare
Candida albicans HCCA Cluster_4 0.019 OF Compare
Candida albicans HCCA Cluster_15 0.201 OF Compare
Candida albicans HCCA Cluster_19 0.023 OF Compare
Candida albicans HCCA Cluster_37 0.021 OF Compare
Coprinopsis cinerea HCCA Cluster_15 0.02 OF Compare
Coprinopsis cinerea HCCA Cluster_26 0.022 OF Compare
Coprinopsis cinerea HCCA Cluster_97 0.022 OF Compare
Coprinopsis cinerea HCCA Cluster_99 0.035 OF Compare
Coprinopsis cinerea HCCA Cluster_120 0.12 OF Compare
Cryptococcus neoformans HCCA Cluster_3 0.071 OF Compare
Cryptococcus neoformans HCCA Cluster_13 0.057 OF Compare
Cryptococcus neoformans HCCA Cluster_55 0.096 OF Compare
Dichomitus squalens HCCA Cluster_9 0.094 OF Compare
Fusarium graminearum HCCA Cluster_21 0.041 OF Compare
Fusarium graminearum HCCA Cluster_37 0.173 OF Compare
Fusarium graminearum HCCA Cluster_77 0.023 OF Compare
Fusarium graminearum HCCA Cluster_95 0.025 OF Compare
Komagataella phaffii HCCA Cluster_1 0.158 OF Compare
Komagataella phaffii HCCA Cluster_10 0.025 OF Compare
Komagataella phaffii HCCA Cluster_17 0.023 OF Compare
Komagataella phaffii HCCA Cluster_37 0.045 OF Compare
Komagataella phaffii HCCA Cluster_39 0.02 OF Compare
Neurospora crassa HCCA Cluster_8 0.019 OF Compare
Neurospora crassa HCCA Cluster_45 0.287 OF Compare
Neurospora crassa HCCA Cluster_50 0.043 OF Compare
Postia placenta HCCA Cluster_36 0.036 OF Compare
Postia placenta HCCA Cluster_66 0.022 OF Compare
Puccinia striiformis HCCA Cluster_13 0.017 OF Compare
Puccinia striiformis HCCA Cluster_21 0.038 OF Compare
Puccinia striiformis HCCA Cluster_55 0.038 OF Compare
Puccinia striiformis HCCA Cluster_77 0.025 OF Compare
Puccinia striiformis HCCA Cluster_98 0.02 OF Compare
Puccinia striiformis HCCA Cluster_112 0.028 OF Compare
Pyricularia oryzae HCCA Cluster_8 0.026 OF Compare
Pyricularia oryzae HCCA Cluster_45 0.041 OF Compare
Pyricularia oryzae HCCA Cluster_60 0.025 OF Compare
Pyricularia oryzae HCCA Cluster_73 0.025 OF Compare
Pyricularia oryzae HCCA Cluster_83 0.029 OF Compare
Pyricularia oryzae HCCA Cluster_85 0.019 OF Compare
Pyricularia oryzae HCCA Cluster_88 0.055 OF Compare
Pyricularia oryzae HCCA Cluster_90 0.021 OF Compare
Schizosaccharomyces pombe HCCA Cluster_2 0.07 OF Compare
Schizosaccharomyces pombe HCCA Cluster_10 0.02 OF Compare
Schizosaccharomyces pombe HCCA Cluster_17 0.104 OF Compare
Schizosaccharomyces pombe HCCA Cluster_35 0.027 OF Compare
Schizosaccharomyces pombe HCCA Cluster_36 0.027 OF Compare
Schizosaccharomyces pombe HCCA Cluster_37 0.019 OF Compare
Trichoderma reesei HCCA Cluster_3 0.138 OF Compare
Trichoderma reesei HCCA Cluster_8 0.02 OF Compare
Trichoderma reesei HCCA Cluster_55 0.017 OF Compare
Trichoderma reesei HCCA Cluster_64 0.048 OF Compare
Trichoderma reesei HCCA Cluster_70 0.026 OF Compare
Trichoderma reesei HCCA Cluster_85 0.028 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_31 0.058 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_54 0.018 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_59 0.039 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_66 0.025 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_100 0.019 OF Compare
Sequences (57) (download table)

InterPro Domains

GO Terms

Family Terms