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GO:0016829: lyase activity (Molecular function)

"Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring." [ISBN:0198547684]


There are 1157 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_7 Saccharomyces cerevisiae 2.52 % 0.001188 0.008364
Cluster_16 Aspergillus fumigatus 3.65 % 0.001833 0.007751
Cluster_63 Aspergillus nidulans 9.23 % 1.7e-05 0.002956
Cluster_56 Aspergillus niger 5.88 % 0.001481 0.010212
Cluster_62 Aspergillus niger 6.15 % 0.001252 0.028794
Cluster_84 Candida albicans 50.0 % 0.012167 0.042583
Cluster_15 Candida albicans 3.14 % 0.002599 0.008849
Cluster_36 Cryptococcus neoformans 7.27 % 0.000612 0.008155
Cluster_97 Cryptococcus neoformans 50.0 % 0.014261 0.042783
Cluster_9 Cryptococcus neoformans 9.09 % 7e-06 0.000626
Cluster_17 Cryptococcus neoformans 8.62 % 5.4e-05 0.003544
Cluster_9 Dichomitus squalens 2.68 % 0.004538 0.017029
Cluster_45 Dichomitus squalens 5.21 % 6.7e-05 0.000544
Cluster_61 Fusarium graminearum 5.88 % 0.000505 0.026265
Cluster_19 Fusarium graminearum 3.09 % 0.003936 0.014478
Cluster_69 Komagataella phaffii 50.0 % 0.013777 0.020665
Cluster_66 Neurospora crassa 5.66 % 0.004275 0.026156
Cluster_50 Neurospora crassa 3.93 % 0.00011 0.001602
Cluster_116 Neurospora crassa 50.0 % 0.01236 0.037081
Cluster_42 Neurospora crassa 6.25 % 0.000648 0.005049
Cluster_45 Neurospora crassa 5.56 % 5.3e-05 0.000249
Cluster_36 Postia placenta 2.68 % 0.00175 0.015448
Cluster_172 Puccinia striiformis 50.0 % 0.005956 0.011911
Cluster_156 Pyricularia oryzae 50.0 % 0.010167 0.030499
Cluster_49 Pyricularia oryzae 4.55 % 0.001039 0.042089
Cluster_146 Pyricularia oryzae 50.0 % 0.010167 0.035974
Cluster_3 Yarrowia lipolytica 2.45 % 0.009096 0.046238
Cluster_18 Yarrowia lipolytica 10.53 % 0.0 2e-06
Cluster_17 Schizosaccharomyces pombe 3.31 % 0.004967 0.045294
Cluster_6 Trichoderma reesei 3.41 % 0.002591 0.031703
Cluster_24 Sclerotinia sclerotiorum 3.87 % 0.000116 0.001137
Sequences (1157) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms