Coexpression cluster: Cluster_52 (HCCA)

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:0005839 proteasome core complex 18.18% (14/77) 7.43 0.0 0.0
GO:0004298 threonine-type endopeptidase activity 18.18% (14/77) 7.43 0.0 0.0
GO:0070003 threonine-type peptidase activity 18.18% (14/77) 7.43 0.0 0.0
GO:0051603 proteolysis involved in cellular protein catabolic process 18.18% (14/77) 6.33 0.0 0.0
GO:0032991 protein-containing complex 27.27% (21/77) 3.85 0.0 0.0
GO:0070011 peptidase activity, acting on L-amino acid peptides 22.08% (17/77) 4.38 0.0 0.0
GO:0008233 peptidase activity 22.08% (17/77) 4.33 0.0 0.0
GO:0004175 endopeptidase activity 18.18% (14/77) 5.03 0.0 0.0
GO:0006508 proteolysis 20.78% (16/77) 4.34 0.0 0.0
GO:0019773 proteasome core complex, alpha-subunit complex 9.09% (7/77) 7.43 0.0 0.0
GO:0140096 catalytic activity, acting on a protein 22.08% (17/77) 3.22 0.0 0.0
GO:0043632 modification-dependent macromolecule catabolic process 9.09% (7/77) 5.72 0.0 0.0
GO:0019941 modification-dependent protein catabolic process 9.09% (7/77) 5.72 0.0 0.0
GO:0006511 ubiquitin-dependent protein catabolic process 9.09% (7/77) 5.72 0.0 0.0
GO:0019538 protein metabolic process 22.08% (17/77) 2.82 0.0 0.0
GO:0044265 cellular macromolecule catabolic process 9.09% (7/77) 5.38 0.0 0.0
GO:0009057 macromolecule catabolic process 9.09% (7/77) 5.11 0.0 0.0
GO:0016787 hydrolase activity 27.27% (21/77) 2.21 0.0 0.0
GO:1901564 organonitrogen compound metabolic process 23.38% (18/77) 2.35 0.0 0.0
GO:0043254 regulation of protein-containing complex assembly 5.19% (4/77) 6.85 0.0 0.0
GO:0032970 regulation of actin filament-based process 5.19% (4/77) 6.85 0.0 0.0
GO:0032956 regulation of actin cytoskeleton organization 5.19% (4/77) 6.85 0.0 0.0
GO:0032535 regulation of cellular component size 5.19% (4/77) 6.85 0.0 0.0
GO:0032271 regulation of protein polymerization 5.19% (4/77) 6.85 0.0 0.0
GO:0030833 regulation of actin filament polymerization 5.19% (4/77) 6.85 0.0 0.0
GO:0030832 regulation of actin filament length 5.19% (4/77) 6.85 0.0 0.0
GO:0008064 regulation of actin polymerization or depolymerization 5.19% (4/77) 6.85 0.0 0.0
GO:0044087 regulation of cellular component biogenesis 5.19% (4/77) 6.85 0.0 0.0
GO:0051493 regulation of cytoskeleton organization 5.19% (4/77) 6.85 0.0 0.0
GO:1902903 regulation of supramolecular fiber organization 5.19% (4/77) 6.85 0.0 0.0
GO:0110053 regulation of actin filament organization 5.19% (4/77) 6.85 0.0 0.0
GO:0090066 regulation of anatomical structure size 5.19% (4/77) 6.85 0.0 0.0
GO:0044248 cellular catabolic process 9.09% (7/77) 4.22 0.0 1e-06
GO:0033043 regulation of organelle organization 5.19% (4/77) 6.11 0.0 2e-06
GO:0051128 regulation of cellular component organization 5.19% (4/77) 5.97 0.0 2e-06
GO:1901575 organic substance catabolic process 9.09% (7/77) 3.87 0.0 3e-06
GO:0009056 catabolic process 9.09% (7/77) 3.78 1e-06 5e-06
GO:0006807 nitrogen compound metabolic process 25.97% (20/77) 1.76 1e-06 6e-06
GO:0003674 molecular_function 59.74% (46/77) 0.84 2e-06 1.3e-05
GO:0005575 cellular_component 29.87% (23/77) 1.48 3e-06 2e-05
GO:0043170 macromolecule metabolic process 22.08% (17/77) 1.76 7e-06 4.6e-05
GO:0008150 biological_process 48.05% (37/77) 0.95 9e-06 5.9e-05
GO:0065008 regulation of biological quality 5.19% (4/77) 4.79 1.2e-05 7.3e-05
GO:1902600 proton transmembrane transport 5.19% (4/77) 4.73 1.4e-05 8.4e-05
GO:0030834 regulation of actin filament depolymerization 2.6% (2/77) 7.43 3.3e-05 0.000152
GO:0008290 F-actin capping protein complex 2.6% (2/77) 7.43 3.3e-05 0.000152
GO:1902904 negative regulation of supramolecular fiber organization 2.6% (2/77) 7.43 3.3e-05 0.000152
GO:0030837 negative regulation of actin filament polymerization 2.6% (2/77) 7.43 3.3e-05 0.000152
GO:0031333 negative regulation of protein-containing complex assembly 2.6% (2/77) 7.43 3.3e-05 0.000152
GO:0032272 negative regulation of protein polymerization 2.6% (2/77) 7.43 3.3e-05 0.000152
GO:1901880 negative regulation of protein depolymerization 2.6% (2/77) 7.43 3.3e-05 0.000152
GO:1901879 regulation of protein depolymerization 2.6% (2/77) 7.43 3.3e-05 0.000152
GO:0043242 negative regulation of protein-containing complex disassembly 2.6% (2/77) 7.43 3.3e-05 0.000152
GO:0051016 barbed-end actin filament capping 2.6% (2/77) 7.43 3.3e-05 0.000152
GO:0051693 actin filament capping 2.6% (2/77) 7.43 3.3e-05 0.000152
GO:0051494 negative regulation of cytoskeleton organization 2.6% (2/77) 7.43 3.3e-05 0.000152
GO:0030835 negative regulation of actin filament depolymerization 2.6% (2/77) 7.43 3.3e-05 0.000152
GO:0015672 monovalent inorganic cation transport 5.19% (4/77) 4.39 3.7e-05 0.000169
GO:0098655 cation transmembrane transport 5.19% (4/77) 4.15 7.3e-05 0.000315
GO:0098662 inorganic cation transmembrane transport 5.19% (4/77) 4.15 7.3e-05 0.000315
GO:0098660 inorganic ion transmembrane transport 5.19% (4/77) 4.15 7.3e-05 0.000315
GO:0015629 actin cytoskeleton 2.6% (2/77) 6.85 9.9e-05 0.000406
GO:0043244 regulation of protein-containing complex disassembly 2.6% (2/77) 6.85 9.9e-05 0.000406
GO:0034220 ion transmembrane transport 5.19% (4/77) 4.04 9.8e-05 0.000416
GO:1902905 positive regulation of supramolecular fiber organization 2.6% (2/77) 6.43 0.000197 0.000672
GO:0051495 positive regulation of cytoskeleton organization 2.6% (2/77) 6.43 0.000197 0.000672
GO:0051129 negative regulation of cellular component organization 2.6% (2/77) 6.43 0.000197 0.000672
GO:0010639 negative regulation of organelle organization 2.6% (2/77) 6.43 0.000197 0.000672
GO:0045010 actin nucleation 2.6% (2/77) 6.43 0.000197 0.000672
GO:0010638 positive regulation of organelle organization 2.6% (2/77) 6.43 0.000197 0.000672
GO:0030838 positive regulation of actin filament polymerization 2.6% (2/77) 6.43 0.000197 0.000672
GO:0031334 positive regulation of protein-containing complex assembly 2.6% (2/77) 6.43 0.000197 0.000672
GO:0005856 cytoskeleton 2.6% (2/77) 6.43 0.000197 0.000672
GO:0032273 positive regulation of protein polymerization 2.6% (2/77) 6.43 0.000197 0.000672
GO:0005885 Arp2/3 protein complex 2.6% (2/77) 6.43 0.000197 0.000672
GO:0034314 Arp2/3 complex-mediated actin nucleation 2.6% (2/77) 6.43 0.000197 0.000672
GO:0044089 positive regulation of cellular component biogenesis 2.6% (2/77) 6.43 0.000197 0.000672
GO:0003824 catalytic activity 35.06% (27/77) 0.97 0.000246 0.00083
GO:0016043 cellular component organization 6.49% (5/77) 3.13 0.000266 0.000874
GO:0008152 metabolic process 32.47% (25/77) 1.02 0.000265 0.000884
GO:0071704 organic substance metabolic process 24.68% (19/77) 1.23 0.000305 0.000991
GO:0051130 positive regulation of cellular component organization 2.6% (2/77) 6.11 0.000327 0.00101
GO:0007015 actin filament organization 2.6% (2/77) 6.11 0.000327 0.00101
GO:0097435 supramolecular fiber organization 2.6% (2/77) 6.11 0.000327 0.00101
GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain 2.6% (2/77) 6.11 0.000327 0.00101
GO:0044238 primary metabolic process 23.38% (18/77) 1.25 0.000365 0.001118
GO:0071840 cellular component organization or biogenesis 6.49% (5/77) 2.97 0.000433 0.001308
GO:0030234 enzyme regulator activity 3.9% (3/77) 4.21 0.000549 0.001641
GO:0009987 cellular process 29.87% (23/77) 1.0 0.00065 0.00192
GO:0048518 positive regulation of biological process 2.6% (2/77) 5.43 0.000904 0.002613
GO:0048522 positive regulation of cellular process 2.6% (2/77) 5.43 0.000904 0.002613
GO:0006812 cation transport 5.19% (4/77) 3.02 0.001469 0.004201
GO:0048523 negative regulation of cellular process 2.6% (2/77) 4.97 0.001756 0.004965
GO:0098772 molecular function regulator 3.9% (3/77) 3.63 0.001816 0.005081
GO:0008144 drug binding 11.69% (9/77) 1.63 0.002402 0.006651
GO:0006886 intracellular protein transport 3.9% (3/77) 3.29 0.003541 0.0097
GO:0048519 negative regulation of biological process 2.6% (2/77) 4.43 0.00376 0.010194
GO:0006811 ion transport 5.19% (4/77) 2.6 0.00427 0.011458
GO:0015833 peptide transport 3.9% (3/77) 3.16 0.004569 0.011896
GO:0042886 amide transport 3.9% (3/77) 3.16 0.004569 0.011896
GO:0015031 protein transport 3.9% (3/77) 3.16 0.004569 0.011896
GO:0016192 vesicle-mediated transport 3.9% (3/77) 3.14 0.004793 0.01236
GO:0045184 establishment of protein localization 3.9% (3/77) 3.11 0.005025 0.012831
GO:0005773 vacuole 1.3% (1/77) 7.43 0.005784 0.013001
GO:0009894 regulation of catabolic process 1.3% (1/77) 7.43 0.005784 0.013001
GO:0042176 regulation of protein catabolic process 1.3% (1/77) 7.43 0.005784 0.013001
GO:1905369 endopeptidase complex 1.3% (1/77) 7.43 0.005784 0.013001
GO:0032324 molybdopterin cofactor biosynthetic process 1.3% (1/77) 7.43 0.005784 0.013001
GO:0051258 protein polymerization 1.3% (1/77) 7.43 0.005784 0.013001
GO:0030041 actin filament polymerization 1.3% (1/77) 7.43 0.005784 0.013001
GO:0004379 glycylpeptide N-tetradecanoyltransferase activity 1.3% (1/77) 7.43 0.005784 0.013001
GO:0000502 proteasome complex 1.3% (1/77) 7.43 0.005784 0.013001
GO:0019107 myristoyltransferase activity 1.3% (1/77) 7.43 0.005784 0.013001
GO:0008154 actin polymerization or depolymerization 1.3% (1/77) 7.43 0.005784 0.013001
GO:0046034 ATP metabolic process 2.6% (2/77) 4.19 0.005298 0.013397
GO:0008104 protein localization 3.9% (3/77) 3.04 0.00576 0.01429
GO:0033036 macromolecule localization 3.9% (3/77) 3.04 0.00576 0.01429
GO:0046907 intracellular transport 3.9% (3/77) 2.93 0.007121 0.015737
GO:0071705 nitrogen compound transport 3.9% (3/77) 2.93 0.007121 0.015737
GO:0071702 organic substance transport 3.9% (3/77) 2.91 0.007414 0.016114
GO:0051649 establishment of localization in cell 3.9% (3/77) 2.91 0.007414 0.016114
GO:0034622 cellular protein-containing complex assembly 2.6% (2/77) 3.73 0.009809 0.021146
GO:0051641 cellular localization 3.9% (3/77) 2.71 0.010739 0.022962
GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1.3% (1/77) 6.43 0.011535 0.023335
GO:0046961 proton-transporting ATPase activity, rotational mechanism 1.3% (1/77) 6.43 0.011535 0.023335
GO:0019211 phosphatase activator activity 1.3% (1/77) 6.43 0.011535 0.023335
GO:0009678 pyrophosphate hydrolysis-driven proton transmembrane transporter activity 1.3% (1/77) 6.43 0.011535 0.023335
GO:0033180 proton-transporting V-type ATPase, V1 domain 1.3% (1/77) 6.43 0.011535 0.023335
GO:0042625 ATPase-coupled ion transmembrane transporter activity 1.3% (1/77) 6.43 0.011535 0.023335
GO:0019829 ATPase-coupled cation transmembrane transporter activity 1.3% (1/77) 6.43 0.011535 0.023335
GO:0065003 protein-containing complex assembly 2.6% (2/77) 3.58 0.012118 0.024328
GO:0008238 exopeptidase activity 2.6% (2/77) 3.53 0.012935 0.025388
GO:0015078 proton transmembrane transporter activity 2.6% (2/77) 3.53 0.012935 0.025388
GO:0005524 ATP binding 9.09% (7/77) 1.48 0.012766 0.025435
GO:0032559 adenyl ribonucleotide binding 9.09% (7/77) 1.44 0.014478 0.028205
GO:0030554 adenyl nucleotide binding 9.09% (7/77) 1.43 0.014806 0.028632
GO:0043933 protein-containing complex subunit organization 2.6% (2/77) 3.39 0.015526 0.029806
GO:0022607 cellular component assembly 2.6% (2/77) 3.3 0.017367 0.032626
GO:0005092 GDP-dissociation inhibitor activity 1.3% (1/77) 5.85 0.017253 0.032643
GO:0070569 uridylyltransferase activity 1.3% (1/77) 5.85 0.017253 0.032643
GO:0015077 monovalent inorganic cation transmembrane transporter activity 2.6% (2/77) 3.26 0.018321 0.034173
GO:0043248 proteasome assembly 1.3% (1/77) 5.43 0.022938 0.041894
GO:0043545 molybdopterin cofactor metabolic process 1.3% (1/77) 5.43 0.022938 0.041894
GO:0051189 prosthetic group metabolic process 1.3% (1/77) 5.43 0.022938 0.041894
GO:0044260 cellular macromolecule metabolic process 10.39% (8/77) 1.16 0.026241 0.047596
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
Saccharomyces cerevisiae HCCA Cluster_24 0.024 OF Compare
Saccharomyces cerevisiae HCCA Cluster_33 0.168 OF Compare
Saccharomyces cerevisiae HCCA Cluster_34 0.035 OF Compare
Saccharomyces cerevisiae HCCA Cluster_46 0.046 OF Compare
Saccharomyces cerevisiae HCCA Cluster_66 0.073 OF Compare
Aspergillus flavus HCCA Cluster_4 0.019 OF Compare
Aspergillus fumigatus HCCA Cluster_33 0.191 OF Compare
Aspergillus fumigatus HCCA Cluster_41 0.032 OF Compare
Aspergillus fumigatus HCCA Cluster_55 0.02 OF Compare
Aspergillus fumigatus HCCA Cluster_60 0.029 OF Compare
Aspergillus fumigatus HCCA Cluster_67 0.024 OF Compare
Aspergillus nidulans HCCA Cluster_18 0.152 OF Compare
Aspergillus nidulans HCCA Cluster_76 0.02 OF Compare
Aspergillus nidulans HCCA Cluster_112 0.042 OF Compare
Aspergillus niger HCCA Cluster_7 0.208 OF Compare
Aspergillus niger HCCA Cluster_62 0.022 OF Compare
Aspergillus niger HCCA Cluster_74 0.018 OF Compare
Aspergillus niger HCCA Cluster_99 0.018 OF Compare
Aspergillus niger HCCA Cluster_111 0.036 OF Compare
Aspergillus niger HCCA Cluster_120 0.022 OF Compare
Aspergillus niger HCCA Cluster_127 0.044 OF Compare
Aspergillus niger HCCA Cluster_128 0.032 OF Compare
Candida albicans HCCA Cluster_6 0.02 OF Compare
Candida albicans HCCA Cluster_8 0.186 OF Compare
Candida albicans HCCA Cluster_19 0.04 OF Compare
Candida albicans HCCA Cluster_25 0.018 OF Compare
Candida albicans HCCA Cluster_28 0.019 OF Compare
Coprinopsis cinerea HCCA Cluster_35 0.028 OF Compare
Coprinopsis cinerea HCCA Cluster_42 0.08 OF Compare
Coprinopsis cinerea HCCA Cluster_83 0.021 OF Compare
Coprinopsis cinerea HCCA Cluster_86 0.024 OF Compare
Cryptococcus neoformans HCCA Cluster_1 0.028 OF Compare
Cryptococcus neoformans HCCA Cluster_3 0.144 OF Compare
Cryptococcus neoformans HCCA Cluster_37 0.033 OF Compare
Dichomitus squalens HCCA Cluster_20 0.02 OF Compare
Dichomitus squalens HCCA Cluster_35 0.034 OF Compare
Dichomitus squalens HCCA Cluster_58 0.039 OF Compare
Dichomitus squalens HCCA Cluster_62 0.036 OF Compare
Komagataella phaffii HCCA Cluster_6 0.113 OF Compare
Komagataella phaffii HCCA Cluster_12 0.141 OF Compare
Komagataella phaffii HCCA Cluster_15 0.02 OF Compare
Komagataella phaffii HCCA Cluster_25 0.018 OF Compare
Neurospora crassa HCCA Cluster_3 0.041 OF Compare
Neurospora crassa HCCA Cluster_11 0.129 OF Compare
Neurospora crassa HCCA Cluster_51 0.074 OF Compare
Neurospora crassa HCCA Cluster_70 0.035 OF Compare
Neurospora crassa HCCA Cluster_75 0.05 OF Compare
Neurospora crassa HCCA Cluster_83 0.025 OF Compare
Neurospora crassa HCCA Cluster_96 0.024 OF Compare
Postia placenta HCCA Cluster_10 0.04 OF Compare
Postia placenta HCCA Cluster_36 0.019 OF Compare
Puccinia striiformis HCCA Cluster_5 0.018 OF Compare
Puccinia striiformis HCCA Cluster_26 0.02 OF Compare
Puccinia striiformis HCCA Cluster_31 0.018 OF Compare
Puccinia striiformis HCCA Cluster_41 0.037 OF Compare
Puccinia striiformis HCCA Cluster_67 0.031 OF Compare
Puccinia striiformis HCCA Cluster_78 0.019 OF Compare
Puccinia striiformis HCCA Cluster_79 0.031 OF Compare
Puccinia striiformis HCCA Cluster_86 0.053 OF Compare
Puccinia striiformis HCCA Cluster_105 0.021 OF Compare
Puccinia striiformis HCCA Cluster_110 0.039 OF Compare
Pyricularia oryzae HCCA Cluster_45 0.052 OF Compare
Pyricularia oryzae HCCA Cluster_90 0.029 OF Compare
Pyricularia oryzae HCCA Cluster_91 0.046 OF Compare
Pyricularia oryzae HCCA Cluster_104 0.019 OF Compare
Pyricularia oryzae HCCA Cluster_124 0.019 OF Compare
Pyricularia oryzae HCCA Cluster_127 0.086 OF Compare
Yarrowia lipolytica HCCA Cluster_1 0.041 OF Compare
Yarrowia lipolytica HCCA Cluster_13 0.1 OF Compare
Yarrowia lipolytica HCCA Cluster_20 0.028 OF Compare
Yarrowia lipolytica HCCA Cluster_27 0.02 OF Compare
Yarrowia lipolytica HCCA Cluster_34 0.023 OF Compare
Schizosaccharomyces pombe HCCA Cluster_14 0.024 OF Compare
Schizosaccharomyces pombe HCCA Cluster_19 0.041 OF Compare
Schizosaccharomyces pombe HCCA Cluster_23 0.059 OF Compare
Schizosaccharomyces pombe HCCA Cluster_32 0.03 OF Compare
Schizosaccharomyces pombe HCCA Cluster_35 0.023 OF Compare
Schizosaccharomyces pombe HCCA Cluster_43 0.029 OF Compare
Schizosaccharomyces pombe HCCA Cluster_50 0.021 OF Compare
Schizosaccharomyces pombe HCCA Cluster_51 0.059 OF Compare
Trichoderma reesei HCCA Cluster_19 0.021 OF Compare
Trichoderma reesei HCCA Cluster_28 0.31 OF Compare
Trichoderma reesei HCCA Cluster_31 0.044 OF Compare
Trichoderma reesei HCCA Cluster_53 0.018 OF Compare
Trichoderma reesei HCCA Cluster_90 0.025 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_12 0.02 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_22 0.05 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_30 0.017 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_52 0.021 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_59 0.031 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_92 0.023 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_96 0.021 OF Compare
Sequences (77) (download table)

InterPro Domains

GO Terms

Family Terms