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GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific (Molecular function)

"A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units." [GOC:txnOH-2018]


There are 2228 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_23 Saccharomyces cerevisiae 7.47 % 0.0 0.0
Cluster_37 Saccharomyces cerevisiae 5.08 % 0.012188 0.034779
Cluster_34 Aspergillus fumigatus 9.4 % 2e-05 0.000201
Cluster_97 Aspergillus fumigatus 9.8 % 0.003277 0.019076
Cluster_84 Aspergillus fumigatus 15.22 % 3e-05 0.002795
Cluster_111 Aspergillus nidulans 20.45 % 2e-06 4.6e-05
Cluster_22 Aspergillus nidulans 19.15 % 0.0 0.0
Cluster_109 Aspergillus nidulans 13.64 % 0.001106 0.047555
Cluster_88 Aspergillus nidulans 10.91 % 0.003545 0.039468
Cluster_30 Aspergillus nidulans 11.01 % 3.7e-05 0.00829
Cluster_57 Aspergillus niger 9.8 % 0.003174 0.023461
Cluster_95 Aspergillus niger 7.58 % 0.009524 0.026952
Cluster_78 Aspergillus niger 7.41 % 0.005169 0.012466
Cluster_112 Aspergillus niger 8.9 % 6e-06 0.000131
Cluster_53 Aspergillus niger 6.9 % 0.007298 0.049445
Cluster_15 Aspergillus niger 5.67 % 0.001596 0.034047
Cluster_124 Aspergillus niger 14.29 % 1e-06 0.000115
Cluster_115 Aspergillus niger 7.59 % 0.000137 0.000716
Cluster_119 Aspergillus niger 7.41 % 0.005169 0.041924
Cluster_33 Candida albicans 4.55 % 0.002593 0.023412
Cluster_57 Candida albicans 14.46 % 0.0 0.0
Cluster_41 Cryptococcus neoformans 9.09 % 2.4e-05 0.002781
Cluster_76 Cryptococcus neoformans 7.55 % 0.005785 0.027096
Cluster_19 Cryptococcus neoformans 5.88 % 0.006002 0.046325
Cluster_38 Cryptococcus neoformans 6.58 % 0.003723 0.031946
Cluster_120 Fusarium graminearum 8.16 % 0.009865 0.031824
Cluster_75 Fusarium graminearum 11.43 % 0.0 0.0
Cluster_96 Fusarium graminearum 13.27 % 0.0 0.0
Cluster_70 Fusarium graminearum 8.64 % 0.00048 0.041998
Cluster_125 Fusarium graminearum 9.68 % 0.000668 0.048285
Cluster_52 Komagataella phaffii 5.17 % 0.001473 0.037124
Cluster_13 Neurospora crassa 4.02 % 0.004998 0.04633
Cluster_20 Neurospora crassa 8.33 % 0.00075 0.021587
Cluster_159 Neurospora crassa 100.0 % 0.000144 0.005312
Cluster_23 Neurospora crassa 4.88 % 0.00364 0.032986
Cluster_316 Puccinia striiformis 50.0 % 0.003311 0.00602
Cluster_93 Puccinia striiformis 2.44 % 0.00807 0.0399
Cluster_103 Puccinia striiformis 3.33 % 0.004398 0.048948
Cluster_4 Pyricularia oryzae 5.85 % 5e-05 0.000479
Cluster_53 Schizosaccharomyces pombe 5.17 % 0.004033 0.025378
Cluster_30 Schizosaccharomyces pombe 3.74 % 0.002812 0.023797
Cluster_75 Trichoderma reesei 9.41 % 0.000191 0.002585
Cluster_34 Trichoderma reesei 6.38 % 0.001367 0.03469
Cluster_88 Trichoderma reesei 12.0 % 0.00033 0.001968
Cluster_24 Trichoderma reesei 10.91 % 1e-06 0.000217
Cluster_86 Sclerotinia sclerotiorum 2.74 % 0.001348 0.005891
Sequences (2228) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms