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GO:0003899: DNA-directed 5'-3' RNA polymerase activity (Molecular function)

"Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'." [EC:2.7.7.6, GOC:pf]


There are 248 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_54 Saccharomyces cerevisiae 8.51 % 2e-06 4.6e-05
Cluster_7 Aspergillus fumigatus 1.32 % 0.003938 0.016565
Cluster_54 Aspergillus fumigatus 2.16 % 0.000114 0.0028
Cluster_64 Aspergillus nidulans 3.64 % 0.002012 0.044672
Cluster_20 Aspergillus niger 2.61 % 0.000147 0.002471
Cluster_84 Aspergillus niger 2.17 % 0.003204 0.009775
Cluster_53 Candida albicans 5.41 % 2.1e-05 0.000212
Cluster_23 Coprinopsis cinerea 2.15 % 0.003025 0.017635
Cluster_83 Coprinopsis cinerea 4.35 % 2.8e-05 0.00292
Cluster_53 Cryptococcus neoformans 3.51 % 0.00515 0.032142
Cluster_24 Dichomitus squalens 1.92 % 4.3e-05 0.000528
Cluster_42 Fusarium graminearum 3.87 % 0.0 0.0
Cluster_47 Komagataella phaffii 6.45 % 1.3e-05 0.000234
Cluster_21 Neurospora crassa 3.57 % 0.000155 0.001348
Cluster_26 Neurospora crassa 3.12 % 0.00023 0.001458
Cluster_29 Neurospora crassa 2.26 % 0.0006 0.003114
Cluster_85 Neurospora crassa 2.02 % 0.007035 0.027943
Cluster_15 Puccinia striiformis 1.12 % 0.02287 0.046037
Cluster_26 Puccinia striiformis 1.52 % 0.013016 0.044867
Cluster_31 Puccinia striiformis 1.92 % 0.001086 0.005349
Cluster_73 Pyricularia oryzae 1.07 % 0.017328 0.049035
Cluster_110 Pyricularia oryzae 4.23 % 5.8e-05 0.003469
Cluster_4 Yarrowia lipolytica 4.41 % 0.000376 0.003699
Cluster_21 Trichoderma reesei 2.86 % 4e-06 8e-05
Cluster_58 Sclerotinia sclerotiorum 2.2 % 0.004129 0.021372
Cluster_26 Sclerotinia sclerotiorum 2.82 % 0.002535 0.012015
Cluster_32 Sclerotinia sclerotiorum 4.23 % 5.2e-05 0.000251
Sequences (248) (download table)

InterPro Domains

GO Terms

Family Terms