Coexpression cluster: Cluster_29 (HCCA)

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:0006260 DNA replication 6.77% (9/133) 5.27 0.0 0.0
GO:0003677 DNA binding 15.79% (21/133) 2.8 0.0 0.0
GO:0006259 DNA metabolic process 9.77% (13/133) 3.82 0.0 0.0
GO:0006270 DNA replication initiation 4.51% (6/133) 6.12 0.0 0.0
GO:0097159 organic cyclic compound binding 32.33% (43/133) 1.52 0.0 0.0
GO:1901363 heterocyclic compound binding 32.33% (43/133) 1.52 0.0 0.0
GO:0000166 nucleotide binding 23.31% (31/133) 1.89 0.0 0.0
GO:1901265 nucleoside phosphate binding 23.31% (31/133) 1.89 0.0 0.0
GO:0005524 ATP binding 18.8% (25/133) 2.19 0.0 0.0
GO:0030554 adenyl nucleotide binding 18.8% (25/133) 2.18 0.0 0.0
GO:0032559 adenyl ribonucleotide binding 18.8% (25/133) 2.18 0.0 0.0
GO:0036094 small molecule binding 23.31% (31/133) 1.79 0.0 0.0
GO:0008144 drug binding 18.8% (25/133) 2.06 0.0 0.0
GO:0035639 purine ribonucleoside triphosphate binding 19.55% (26/133) 1.97 0.0 0.0
GO:0032555 purine ribonucleotide binding 19.55% (26/133) 1.95 0.0 0.0
GO:0005488 binding 40.6% (54/133) 1.13 0.0 0.0
GO:0017076 purine nucleotide binding 19.55% (26/133) 1.94 0.0 0.0
GO:0044260 cellular macromolecule metabolic process 20.3% (27/133) 1.87 0.0 0.0
GO:0032553 ribonucleotide binding 19.55% (26/133) 1.93 0.0 0.0
GO:0097367 carbohydrate derivative binding 19.55% (26/133) 1.92 0.0 0.0
GO:0003676 nucleic acid binding 18.8% (25/133) 1.94 0.0 0.0
GO:0043168 anion binding 21.05% (28/133) 1.67 0.0 0.0
GO:0005643 nuclear pore 3.01% (4/133) 6.02 0.0 1e-06
GO:0043170 macromolecule metabolic process 20.3% (27/133) 1.41 2e-06 2.6e-05
GO:0006325 chromatin organization 3.76% (5/133) 4.14 7e-06 7.6e-05
GO:0009059 macromolecule biosynthetic process 10.53% (14/133) 2.04 7e-06 7.8e-05
GO:0090304 nucleic acid metabolic process 12.03% (16/133) 1.86 8e-06 7.9e-05
GO:0017056 structural constituent of nuclear pore 2.26% (3/133) 5.93 7e-06 8.1e-05
GO:0008094 DNA-dependent ATPase activity 3.01% (4/133) 4.76 1e-05 9.7e-05
GO:0043229 intracellular organelle 11.28% (15/133) 1.89 1.2e-05 0.000106
GO:0043226 organelle 11.28% (15/133) 1.89 1.2e-05 0.000106
GO:0043167 ion binding 23.31% (31/133) 1.14 1.6e-05 0.000136
GO:0140097 catalytic activity, acting on DNA 3.76% (5/133) 3.86 2e-05 0.000174
GO:0009987 cellular process 30.08% (40/133) 0.92 2.7e-05 0.000226
GO:0005634 nucleus 7.52% (10/133) 2.31 3.3e-05 0.000267
GO:0016043 cellular component organization 6.02% (8/133) 2.59 5.3e-05 0.000415
GO:0006139 nucleobase-containing compound metabolic process 12.03% (16/133) 1.63 5.6e-05 0.000424
GO:0043227 membrane-bounded organelle 7.52% (10/133) 2.1 0.000116 0.000809
GO:0043231 intracellular membrane-bounded organelle 7.52% (10/133) 2.1 0.000116 0.000809
GO:0071840 cellular component organization or biogenesis 6.02% (8/133) 2.44 0.000113 0.00083
GO:0016779 nucleotidyltransferase activity 3.76% (5/133) 3.34 0.000122 0.000832
GO:0006725 cellular aromatic compound metabolic process 12.03% (16/133) 1.5 0.000162 0.000909
GO:0006269 DNA replication, synthesis of RNA primer 1.5% (2/133) 6.34 0.00015 0.000915
GO:0031262 Ndc80 complex 1.5% (2/133) 6.34 0.00015 0.000915
GO:0006275 regulation of DNA replication 1.5% (2/133) 6.34 0.00015 0.000915
GO:0044237 cellular metabolic process 20.3% (27/133) 1.06 0.000161 0.00092
GO:0032991 protein-containing complex 9.02% (12/133) 1.81 0.000159 0.000929
GO:0046483 heterocycle metabolic process 12.03% (16/133) 1.5 0.000158 0.000943
GO:0005694 chromosome 2.26% (3/133) 4.76 0.000145 0.000944
GO:0003678 DNA helicase activity 2.26% (3/133) 4.76 0.000145 0.000944
GO:1901360 organic cyclic compound metabolic process 12.03% (16/133) 1.44 0.000251 0.001378
GO:0034645 cellular macromolecule biosynthetic process 8.27% (11/133) 1.82 0.000293 0.001577
GO:0003887 DNA-directed DNA polymerase activity 1.5% (2/133) 5.76 0.000447 0.002363
GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2.26% (3/133) 4.12 0.0006 0.003114
GO:0044249 cellular biosynthetic process 10.53% (14/133) 1.41 0.000764 0.003887
GO:0022402 cell cycle process 2.26% (3/133) 3.93 0.000907 0.004306
GO:0006974 cellular response to DNA damage stimulus 3.76% (5/133) 2.74 0.000896 0.004327
GO:0007059 chromosome segregation 1.5% (2/133) 5.34 0.000887 0.004359
GO:0000775 chromosome, centromeric region 1.5% (2/133) 5.34 0.000887 0.004359
GO:1901576 organic substance biosynthetic process 10.53% (14/133) 1.38 0.000935 0.004363
GO:0097747 RNA polymerase activity 2.26% (3/133) 3.84 0.001092 0.004853
GO:0034062 5'-3' RNA polymerase activity 2.26% (3/133) 3.84 0.001092 0.004853
GO:0003674 molecular_function 46.62% (62/133) 0.48 0.001063 0.004877
GO:0033554 cellular response to stress 3.76% (5/133) 2.67 0.001116 0.00488
GO:0051716 cellular response to stimulus 3.76% (5/133) 2.64 0.001197 0.005155
GO:0004386 helicase activity 2.26% (3/133) 3.61 0.001782 0.007559
GO:0006950 response to stress 3.76% (5/133) 2.5 0.001893 0.007911
GO:0034641 cellular nitrogen compound metabolic process 12.03% (16/133) 1.16 0.002033 0.00837
GO:0006338 chromatin remodeling 1.5% (2/133) 4.76 0.002183 0.008608
GO:0034061 DNA polymerase activity 1.5% (2/133) 4.76 0.002183 0.008608
GO:0098687 chromosomal region 1.5% (2/133) 4.76 0.002183 0.008608
GO:0009058 biosynthetic process 10.53% (14/133) 1.24 0.002314 0.008997
GO:0050896 response to stimulus 3.76% (5/133) 2.42 0.002404 0.00922
GO:0071704 organic substance metabolic process 20.3% (27/133) 0.79 0.00293 0.01094
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 5.26% (7/133) 1.89 0.002896 0.010958
GO:0008608 attachment of spindle microtubules to kinetochore 1.5% (2/133) 4.54 0.003031 0.011167
GO:0016817 hydrolase activity, acting on acid anhydrides 5.26% (7/133) 1.86 0.003225 0.011726
GO:0051276 chromosome organization 2.26% (3/133) 3.29 0.003437 0.012339
GO:0005575 cellular_component 18.8% (25/133) 0.8 0.00382 0.013539
GO:0006281 DNA repair 3.01% (4/133) 2.56 0.004602 0.016108
GO:0030983 mismatched DNA binding 1.5% (2/133) 4.02 0.00634 0.021649
GO:0003690 double-stranded DNA binding 1.5% (2/133) 4.02 0.00634 0.021649
GO:0006298 mismatch repair 1.5% (2/133) 3.89 0.007687 0.025931
GO:0016887 ATPase activity 3.01% (4/133) 2.34 0.007877 0.026258
GO:0048523 negative regulation of cellular process 1.5% (2/133) 3.76 0.00915 0.030142
GO:0042592 homeostatic process 1.5% (2/133) 3.54 0.012415 0.030763
GO:0003689 DNA clamp loader activity 0.75% (1/133) 6.34 0.012306 0.030764
GO:1903046 meiotic cell cycle process 0.75% (1/133) 6.34 0.012306 0.030764
GO:1905463 negative regulation of DNA duplex unwinding 0.75% (1/133) 6.34 0.012306 0.030764
GO:1905462 regulation of DNA duplex unwinding 0.75% (1/133) 6.34 0.012306 0.030764
GO:0061731 ribonucleoside-diphosphate reductase activity 0.75% (1/133) 6.34 0.012306 0.030764
GO:0090329 regulation of DNA-dependent DNA replication 0.75% (1/133) 6.34 0.012306 0.030764
GO:0016728 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor 0.75% (1/133) 6.34 0.012306 0.030764
GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 0.75% (1/133) 6.34 0.012306 0.030764
GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor 0.75% (1/133) 6.34 0.012306 0.030764
GO:2000104 negative regulation of DNA-dependent DNA replication 0.75% (1/133) 6.34 0.012306 0.030764
GO:0045132 meiotic chromosome segregation 0.75% (1/133) 6.34 0.012306 0.030764
GO:0033170 protein-DNA loading ATPase activity 0.75% (1/133) 6.34 0.012306 0.030764
GO:0005663 DNA replication factor C complex 0.75% (1/133) 6.34 0.012306 0.030764
GO:0006333 chromatin assembly or disassembly 0.75% (1/133) 6.34 0.012306 0.030764
GO:0051315 attachment of mitotic spindle microtubules to kinetochore 0.75% (1/133) 6.34 0.012306 0.030764
GO:0048478 replication fork protection 0.75% (1/133) 6.34 0.012306 0.030764
GO:0016973 poly(A)+ mRNA export from nucleus 0.75% (1/133) 6.34 0.012306 0.030764
GO:0003896 DNA primase activity 0.75% (1/133) 6.34 0.012306 0.030764
GO:0051301 cell division 0.75% (1/133) 6.34 0.012306 0.030764
GO:0031965 nuclear membrane 0.75% (1/133) 6.34 0.012306 0.030764
GO:0008156 negative regulation of DNA replication 0.75% (1/133) 6.34 0.012306 0.030764
GO:0042555 MCM complex 0.75% (1/133) 6.34 0.012306 0.030764
GO:1905774 regulation of DNA helicase activity 0.75% (1/133) 6.34 0.012306 0.030764
GO:0051097 negative regulation of helicase activity 0.75% (1/133) 6.34 0.012306 0.030764
GO:0051095 regulation of helicase activity 0.75% (1/133) 6.34 0.012306 0.030764
GO:0031491 nucleosome binding 0.75% (1/133) 6.34 0.012306 0.030764
GO:1905775 negative regulation of DNA helicase activity 0.75% (1/133) 6.34 0.012306 0.030764
GO:0048519 negative regulation of biological process 1.5% (2/133) 3.34 0.016111 0.039571
GO:0006996 organelle organization 2.26% (3/133) 2.37 0.019923 0.048508
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
Saccharomyces cerevisiae HCCA Cluster_5 0.02 OF Compare
Saccharomyces cerevisiae HCCA Cluster_12 0.028 OF Compare
Saccharomyces cerevisiae HCCA Cluster_13 0.023 OF Compare
Saccharomyces cerevisiae HCCA Cluster_37 0.075 OF Compare
Saccharomyces cerevisiae HCCA Cluster_41 0.07 OF Compare
Saccharomyces cerevisiae HCCA Cluster_43 0.034 OF Compare
Saccharomyces cerevisiae HCCA Cluster_48 0.024 OF Compare
Saccharomyces cerevisiae HCCA Cluster_58 0.024 OF Compare
Saccharomyces cerevisiae HCCA Cluster_59 0.059 OF Compare
Saccharomyces cerevisiae HCCA Cluster_63 0.034 OF Compare
Aspergillus flavus HCCA Cluster_4 0.055 OF Compare
Aspergillus fumigatus HCCA Cluster_24 0.17 OF Compare
Aspergillus fumigatus HCCA Cluster_51 0.057 OF Compare
Aspergillus fumigatus HCCA Cluster_54 0.023 OF Compare
Aspergillus fumigatus HCCA Cluster_92 0.034 OF Compare
Aspergillus nidulans HCCA Cluster_18 0.089 OF Compare
Aspergillus nidulans HCCA Cluster_38 0.031 OF Compare
Aspergillus nidulans HCCA Cluster_49 0.022 OF Compare
Aspergillus nidulans HCCA Cluster_68 0.109 OF Compare
Aspergillus nidulans HCCA Cluster_74 0.025 OF Compare
Aspergillus nidulans HCCA Cluster_92 0.034 OF Compare
Aspergillus nidulans HCCA Cluster_97 0.065 OF Compare
Aspergillus nidulans HCCA Cluster_100 0.036 OF Compare
Aspergillus nidulans HCCA Cluster_112 0.023 OF Compare
Aspergillus niger HCCA Cluster_20 0.109 OF Compare
Aspergillus niger HCCA Cluster_26 0.047 OF Compare
Aspergillus niger HCCA Cluster_32 0.034 OF Compare
Aspergillus niger HCCA Cluster_48 0.03 OF Compare
Aspergillus niger HCCA Cluster_58 0.027 OF Compare
Aspergillus niger HCCA Cluster_74 0.023 OF Compare
Aspergillus niger HCCA Cluster_89 0.182 OF Compare
Aspergillus niger HCCA Cluster_134 0.018 OF Compare
Candida albicans HCCA Cluster_1 0.122 OF Compare
Candida albicans HCCA Cluster_25 0.022 OF Compare
Candida albicans HCCA Cluster_28 0.019 OF Compare
Candida albicans HCCA Cluster_38 0.043 OF Compare
Candida albicans HCCA Cluster_42 0.025 OF Compare
Candida albicans HCCA Cluster_51 0.037 OF Compare
Candida albicans HCCA Cluster_55 0.031 OF Compare
Candida albicans HCCA Cluster_59 0.028 OF Compare
Candida albicans HCCA Cluster_63 0.023 OF Compare
Candida albicans HCCA Cluster_67 0.017 OF Compare
Coprinopsis cinerea HCCA Cluster_20 0.018 OF Compare
Coprinopsis cinerea HCCA Cluster_25 0.023 OF Compare
Coprinopsis cinerea HCCA Cluster_34 0.069 OF Compare
Coprinopsis cinerea HCCA Cluster_47 0.028 OF Compare
Coprinopsis cinerea HCCA Cluster_83 0.064 OF Compare
Coprinopsis cinerea HCCA Cluster_108 0.055 OF Compare
Coprinopsis cinerea HCCA Cluster_136 0.021 OF Compare
Coprinopsis cinerea HCCA Cluster_137 0.054 OF Compare
Cryptococcus neoformans HCCA Cluster_1 0.019 OF Compare
Cryptococcus neoformans HCCA Cluster_21 0.153 OF Compare
Cryptococcus neoformans HCCA Cluster_38 0.02 OF Compare
Cryptococcus neoformans HCCA Cluster_46 0.026 OF Compare
Cryptococcus neoformans HCCA Cluster_56 0.028 OF Compare
Cryptococcus neoformans HCCA Cluster_57 0.023 OF Compare
Cryptococcus neoformans HCCA Cluster_62 0.025 OF Compare
Cryptococcus neoformans HCCA Cluster_70 0.019 OF Compare
Cryptococcus neoformans HCCA Cluster_74 0.02 OF Compare
Cryptococcus neoformans HCCA Cluster_80 0.018 OF Compare
Dichomitus squalens HCCA Cluster_24 0.021 OF Compare
Dichomitus squalens HCCA Cluster_35 0.03 OF Compare
Fusarium graminearum HCCA Cluster_10 0.137 OF Compare
Fusarium graminearum HCCA Cluster_48 0.07 OF Compare
Fusarium graminearum HCCA Cluster_84 0.046 OF Compare
Fusarium graminearum HCCA Cluster_99 0.124 OF Compare
Komagataella phaffii HCCA Cluster_1 0.025 OF Compare
Komagataella phaffii HCCA Cluster_9 0.031 OF Compare
Komagataella phaffii HCCA Cluster_22 0.151 OF Compare
Komagataella phaffii HCCA Cluster_25 0.018 OF Compare
Komagataella phaffii HCCA Cluster_30 0.018 OF Compare
Komagataella phaffii HCCA Cluster_33 0.028 OF Compare
Komagataella phaffii HCCA Cluster_36 0.033 OF Compare
Komagataella phaffii HCCA Cluster_46 0.029 OF Compare
Komagataella phaffii HCCA Cluster_47 0.032 OF Compare
Komagataella phaffii HCCA Cluster_54 0.021 OF Compare
Postia placenta HCCA Cluster_3 0.022 OF Compare
Postia placenta HCCA Cluster_41 0.02 OF Compare
Postia placenta HCCA Cluster_49 0.031 OF Compare
Postia placenta HCCA Cluster_65 0.02 OF Compare
Puccinia striiformis HCCA Cluster_2 0.024 OF Compare
Puccinia striiformis HCCA Cluster_5 0.026 OF Compare
Puccinia striiformis HCCA Cluster_26 0.028 OF Compare
Puccinia striiformis HCCA Cluster_31 0.052 OF Compare
Puccinia striiformis HCCA Cluster_59 0.021 OF Compare
Puccinia striiformis HCCA Cluster_78 0.019 OF Compare
Puccinia striiformis HCCA Cluster_94 0.04 OF Compare
Pyricularia oryzae HCCA Cluster_10 0.172 OF Compare
Pyricularia oryzae HCCA Cluster_23 0.022 OF Compare
Pyricularia oryzae HCCA Cluster_63 0.018 OF Compare
Pyricularia oryzae HCCA Cluster_73 0.064 OF Compare
Pyricularia oryzae HCCA Cluster_91 0.033 OF Compare
Pyricularia oryzae HCCA Cluster_106 0.019 OF Compare
Pyricularia oryzae HCCA Cluster_110 0.026 OF Compare
Yarrowia lipolytica HCCA Cluster_12 0.237 OF Compare
Yarrowia lipolytica HCCA Cluster_16 0.023 OF Compare
Yarrowia lipolytica HCCA Cluster_25 0.046 OF Compare
Yarrowia lipolytica HCCA Cluster_38 0.022 OF Compare
Yarrowia lipolytica HCCA Cluster_45 0.046 OF Compare
Yarrowia lipolytica HCCA Cluster_68 0.017 OF Compare
Schizosaccharomyces pombe HCCA Cluster_3 0.027 OF Compare
Schizosaccharomyces pombe HCCA Cluster_12 0.023 OF Compare
Schizosaccharomyces pombe HCCA Cluster_14 0.032 OF Compare
Schizosaccharomyces pombe HCCA Cluster_18 0.058 OF Compare
Schizosaccharomyces pombe HCCA Cluster_23 0.023 OF Compare
Schizosaccharomyces pombe HCCA Cluster_29 0.047 OF Compare
Schizosaccharomyces pombe HCCA Cluster_30 0.022 OF Compare
Schizosaccharomyces pombe HCCA Cluster_38 0.044 OF Compare
Schizosaccharomyces pombe HCCA Cluster_41 0.045 OF Compare
Schizosaccharomyces pombe HCCA Cluster_44 0.026 OF Compare
Schizosaccharomyces pombe HCCA Cluster_53 0.039 OF Compare
Trichoderma reesei HCCA Cluster_2 0.041 OF Compare
Trichoderma reesei HCCA Cluster_16 0.129 OF Compare
Trichoderma reesei HCCA Cluster_19 0.058 OF Compare
Trichoderma reesei HCCA Cluster_38 0.036 OF Compare
Trichoderma reesei HCCA Cluster_47 0.026 OF Compare
Trichoderma reesei HCCA Cluster_70 0.033 OF Compare
Trichoderma reesei HCCA Cluster_89 0.03 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_26 0.093 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_27 0.14 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_56 0.051 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_59 0.018 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_79 0.039 OF Compare
Sclerotinia sclerotiorum HCCA Cluster_87 0.022 OF Compare
Sequences (133) (download table)

InterPro Domains

GO Terms

Family Terms