AFR98348

Description : leucine-tRNA ligase;Anticodon-binding domain of tRNA;tRNA synthetases class I (I, L, M and V)

Gene families : OG_03_0003177 (OF) Phylogenetic Tree(s): OG0003177_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AFR98348
Cluster	HCCA: Cluster_55

Target	Alias	Description	ECC score	Gene Family Method
AOA69702	No alias	Aminoacyl-tRNA synthetase, class Ia	0.06	OF
CAG79959	No alias	Aminoacyl-tRNA synthetase, class Ia	0.11	OF
CBF75578	No alias	leucyl-tRNA synthetase	0.18	OF
EAA33982	No alias	Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase,...	0.11	OF
EAL89103	No alias	leucyl-tRNA synthetase	0.17	OF
EAU87569	No alias	leucine-tRNA ligase	0.05	OF
EGR48778	No alias	Aminoacyl-tRNA synthetase, class Ia	0.11	OF
EJF59260	No alias	Anticodon-binding domain of tRNA	0.04	OF
ESU12052	No alias	leucyl-tRNA synthetase	0.1	OF
KHC71145	No alias	leucine-tRNA ligase;Anticodon-binding domain of...	0.14	OF
MGG_02432T0	No alias	Leucyl-tRNA synthetase [Source:UniProtKB/TrEMBL;Acc:G4MRI0]	0.11	OF
POW13159	No alias	Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase,...	0.02	OF
SPAC26F1.13c.1	No alias	cytoplasmic leucine-tRNA ligase Lrs1 (predicted)...	0.12	OF
YPL160W	No alias	Cytosolic leucyl tRNA synthetase; ligates leucine to the...	0.13	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006418	tRNA aminoacylation for protein translation	IEA	Interproscan
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043038	amino acid activation	None	Extended
BP	GO:0043039	tRNA aminoacylation	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR013155	M/V/L/I-tRNA-synth_anticd-bd	827	964
IPR002300	aa-tRNA-synth_Ia	216	789
IPR002300	aa-tRNA-synth_Ia	68	137

External Links

No external refs found!

AFR98348

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation