YPR006C

Description : 2-methylisocitrate lyase of the mitochondrial matrix; functions in the methylcitrate cycle to catalyze the conversion of 2-methylisocitrate to succinate and pyruvate; ICL2 transcription is repressed by glucose and induced by ethanol [Source:SGD;Acc:S000006210]

Gene families : OG_03_0000522 (OF) Phylogenetic Tree(s): OG0000522_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YPR006C
Cluster	HCCA: Cluster_26

Target	Alias	Description	ECC score	Gene Family Method
AFR94564	No alias	isocitrate lyase;Isocitrate lyase family	0.05	OF
AOA66524	No alias	Isocitrate lyase	0.03	OF
CAG78931	No alias	Isocitrate lyase	0.03	OF
CAG82243	No alias	Isocitrate lyase	0.08	OF
CAK43977	No alias	Isocitrate lyase family	0.06	OF
CAK48502	No alias	Isocitrate lyase family	0.08	OF
CBF78090	No alias	Methylisocitrate lyase Precursor	0.06	OF
CBF81510	No alias	Isocitrate lyase	0.03	OF
EAA31618	No alias	Isocitrate lyase	0.04	OF
EAA35839	No alias	Isocitrate lyase	0.1	OF
EAL85752	No alias	isocitrate lyase	0.11	OF
EAL89442	No alias	isocitrate lyase AcuD	0.07	OF
EDO02424	No alias	Isocitrate lyase	0.02	OF
EDO02499	No alias	Isocitrate lyase	0.05	OF
EGR46187	No alias	Isocitrate lyase	0.03	OF
EGR50628	No alias	Isocitrate lyase	0.04	OF
EJF57125	No alias	Isocitrate lyase family	0.02	OF
ESU05304	No alias	isocitrate lyase	0.04	OF
MGG_02616T0	No alias	Isocitrate lyase [Source:UniProtKB/TrEMBL;Acc:G5EH03]	0.04	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004451	isocitrate lyase activity	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016829	lyase activity	None	Extended
MF	GO:0016830	carbon-carbon lyase activity	None	Extended
MF	GO:0016833	oxo-acid-lyase activity	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	IEA	Interproscan
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR006254	Isocitrate_lyase	47	575

External Links

No external refs found!

YPR006C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation