YPL160W

Description : Cytosolic leucyl tRNA synthetase; ligates leucine to the appropriate tRNA; human homolog LARS can complement yeast temperature-sensitive mutant at restrictive temperature [Source:SGD;Acc:S000006081]

Gene families : OG_03_0003177 (OF) Phylogenetic Tree(s): OG0003177_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YPL160W
Cluster	HCCA: Cluster_8

Target	Alias	Description	ECC score	Gene Family Method
AFR98348	No alias	leucine-tRNA ligase;Anticodon-binding domain of...	0.13	OF
AOA69702	No alias	Aminoacyl-tRNA synthetase, class Ia	0.1	OF
CAG79959	No alias	Aminoacyl-tRNA synthetase, class Ia	0.16	OF
CBF75578	No alias	leucyl-tRNA synthetase	0.14	OF
EAA33982	No alias	Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase,...	0.09	OF
EAL89103	No alias	leucyl-tRNA synthetase	0.18	OF
EAU87569	No alias	leucine-tRNA ligase	0.06	OF
EGR48778	No alias	Aminoacyl-tRNA synthetase, class Ia	0.13	OF
EJF59260	No alias	Anticodon-binding domain of tRNA	0.04	OF
ESU12052	No alias	leucyl-tRNA synthetase	0.09	OF
KHC71145	No alias	leucine-tRNA ligase;Anticodon-binding domain of...	0.2	OF
MGG_02432T0	No alias	Leucyl-tRNA synthetase [Source:UniProtKB/TrEMBL;Acc:G4MRI0]	0.17	OF
POW13159	No alias	Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase,...	0.06	OF
SPAC26F1.13c.1	No alias	cytoplasmic leucine-tRNA ligase Lrs1 (predicted)...	0.26	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006418	tRNA aminoacylation for protein translation	IEA	Interproscan
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043038	amino acid activation	None	Extended
BP	GO:0043039	tRNA aminoacylation	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR013155	M/V/L/I-tRNA-synth_anticd-bd	809	932
IPR002300	aa-tRNA-synth_Ia	52	116
IPR002300	aa-tRNA-synth_Ia	192	769

External Links

No external refs found!

YPL160W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation