YPL149W


Description : Conserved protein involved in autophagy and the Cvt pathway; undergoes conjugation with Atg12p to form a complex involved in Atg8p lipidation; Atg5p-Atg12p conjugate enhances E2 activity of Atg3 by rearranging its catalytic site, also forms a complex with Atg16p; the Atg5-Atg12/Atg16 complex binds to membranes and is essential for autophagosome formation; also involved in methionine restriction extension of chronological lifespan in an autophagy-dependent manner [Source:SGD;Acc:S000006070]


Gene families : OG_03_0002865 (OF) Phylogenetic Tree(s): OG0002865_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YPL149W
Cluster HCCA: Cluster_65


Type GO Term Name Evidence Source
CC GO:0005737 cytoplasm IEA Interproscan
BP GO:0006914 autophagy IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR007239 Atg5 83 281
No external refs found!