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Expression profile for YPL149W (YPL149W)

Description : Conserved protein involved in autophagy and the Cvt pathway; undergoes conjugation with Atg12p to form a complex involved in Atg8p lipidation; Atg5p-Atg12p conjugate enhances E2 activity of Atg3 by rearranging its catalytic site, also forms a complex with Atg16p; the Atg5-Atg12/Atg16 complex binds to membranes and is essential for autophagosome formation; also involved in methionine restriction extension of chronological lifespan in an autophagy-dependent manner [Source:SGD;Acc:S000006070]

Sample enrichment: rap,YPD,WT (SPM: 0.46, entropy: 2.83, tau: 0.78)
Perturbation specificity: Rapamycin (SPM: 0.68, entropy: 2.42, tau: 0.74)