YNL189W

Description : Karyopherin alpha homolog; forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; involved in cotranslational protein degradation; binds ribosome-bound nascent polypeptides; Srp1p and Sts1p couple proteasomes to nascent polypeptides emerging from the ribosome for cotranslational degradation [Source:SGD;Acc:S000005133]

Gene families : OG_03_0002186 (OF) Phylogenetic Tree(s): OG0002186_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YNL189W
Cluster	HCCA: Cluster_13

Target	Alias	Description	ECC score	Gene Family Method
AOA68405	No alias	Importin-alpha, importin-beta-binding domain	0.03	OF
CAG78805	No alias	Importin-alpha, importin-beta-binding domain	0.03	OF
CAK42596	No alias	Armadillo/beta-catenin-like repeat	0.02	OF
EAU93208	No alias	importin alpha protein	0.01	OF
KHC74929	No alias	importin subunit alpha;Importin beta binding...	0.02	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IEA	Interproscan
BP	GO:0006606	protein import into nucleus	IEA	Interproscan
BP	GO:0006810	transport	None	Extended
BP	GO:0006886	intracellular protein transport	None	Extended
BP	GO:0006913	nucleocytoplasmic transport	None	Extended
BP	GO:0008104	protein localization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0015031	protein transport	None	Extended
BP	GO:0015833	peptide transport	None	Extended
BP	GO:0017038	protein import	None	Extended
BP	GO:0033036	macromolecule localization	None	Extended
BP	GO:0033365	protein localization to organelle	None	Extended
BP	GO:0034504	protein localization to nucleus	None	Extended
BP	GO:0034613	cellular protein localization	None	Extended
BP	GO:0042886	amide transport	None	Extended
BP	GO:0045184	establishment of protein localization	None	Extended
BP	GO:0046907	intracellular transport	None	Extended
BP	GO:0051169	nuclear transport	None	Extended
BP	GO:0051170	import into nucleus	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0051641	cellular localization	None	Extended
BP	GO:0051649	establishment of localization in cell	None	Extended
MF	GO:0061608	nuclear import signal receptor activity	IEA	Interproscan
BP	GO:0070727	cellular macromolecule localization	None	Extended
BP	GO:0071702	organic substance transport	None	Extended
BP	GO:0071705	nitrogen compound transport	None	Extended
BP	GO:0072594	establishment of protein localization to organelle	None	Extended
MF	GO:0140142	nucleocytoplasmic carrier activity	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR002652	Importin-a_IBB	17	108
IPR000225	Armadillo	418	455
IPR000225	Armadillo	205	244
IPR000225	Armadillo	330	370
IPR000225	Armadillo	372	411
IPR000225	Armadillo	248	286
IPR000225	Armadillo	121	160
IPR000225	Armadillo	289	327
IPR000225	Armadillo	163	201
IPR032413	Arm_3	471	523

External Links

No external refs found!

YNL189W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation