YLR451W

Description : Zinc-knuckle transcription factor, repressor and activator; regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; acts as a repressor in leucine-replete conditions and as an activator in the presence of alpha-isopropylmalate, an intermediate in leucine biosynthesis that accumulates during leucine starvation [Source:SGD;Acc:S000004443]

Gene families : OG_03_0000511 (OF) Phylogenetic Tree(s): OG0000511_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YLR451W
Cluster	HCCA: Cluster_59

Target	Alias	Description	ECC score	Gene Family Method
KHC71182	No alias	hypothetical protein;Fungal specific transcription...	0.02	OF
KHC75119	No alias	transcriptional regulatory protein LEU3;Fungal...	0.04	OF
MGG_00672T0	No alias	C6 zinc finger domain-containing protein...	0.02	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003700	DNA-binding transcription factor activity	None	Extended
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006355	regulation of transcription, DNA-templated	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
MF	GO:0008270	zinc ion binding	IEA	Interproscan
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
CC	GO:0018995	host cellular component	None	Extended
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
CC	GO:0033643	host cell part	None	Extended
CC	GO:0033646	host intracellular part	None	Extended
CC	GO:0033647	host intracellular organelle	None	Extended
CC	GO:0033648	host intracellular membrane-bounded organelle	None	Extended
CC	GO:0042025	host cell nucleus	IEA	Interproscan
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051252	regulation of RNA metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
MF	GO:0140110	transcription regulator activity	None	Extended
BP	GO:1903506	regulation of nucleic acid-templated transcription	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended
BP	GO:2001141	regulation of RNA biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR001138	Zn2-C6_fun-type_DNA-bd	36	75

External Links

No external refs found!

YLR451W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation