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  5. YLL018C

YLL018C


Description : Aspartyl-tRNA synthetase, primarily cytoplasmic; homodimeric enzyme that catalyzes the specific aspartylation of tRNA(Asp); class II aminoacyl tRNA synthetase; binding to its own mRNA may confer autoregulation; shares five highly conserved amino acids with human that when mutated cause leukoencephalopathy characterized by hypomyelination with brain stem and spinal cord involvement and leg spasticity (HBSL) [Source:SGD;Acc:S000003941]


Gene families : OG_03_0000561 (OF) Phylogenetic Tree(s): OG0000561_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YLL018C
Cluster HCCA: Cluster_7

Target Alias Description ECC score Gene Family Method Actions
AFR94626 No alias aspartate-tRNA(Asn) ligase;tRNA synthetases class II (D, K and N) 0.02 OF
AOA65984 No alias Aminoacyl-tRNA synthetase, class II (D/K/N) 0.07 OF
CAG81342 No alias Aminoacyl-tRNA synthetase, class II (D/K/N) 0.03 OF
CAK48970 No alias tRNA synthetases class II (D, K and N) 0.13 OF
CBF77275 No alias aspartyl-tRNA synthetase Dps1, putative 0.06 OF
EAL87356 No alias aspartyl-tRNA synthetase Dps1, putative 0.13 OF
EAU93029 No alias aspartate-tRNA ligase 0.04 OF
EDN93572 No alias Aminoacyl-tRNA synthetase, class II (D/K/N) 0.08 OF
EED77558 No alias OB-fold nucleic acid binding domain, AA-tRNA synthetase-type 0.04 OF
ESU08534 No alias Aminoacyl-tRNA synthetase, class II (D/K/N) 0.02 OF
KHC71277 No alias aspartyl-tRNA synthetase, cytoplasmic;OB-fold nucleic... 0.05 OF
MGG_12574T0 No alias Aspartyl-tRNA synthetase [Source:UniProtKB/TrEMBL;Acc:G4NLR3] 0.04 OF
POW12880 No alias Aminoacyl-tRNA synthetase, class II (D/K/N);OB-fold... 0.04 OF
SPCC1223.07c.1 No alias cytoplasmic aspartate-tRNA ligase Drs1 (predicted)... 0.11 OF

Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEA Interproscan
MF GO:0003676 nucleic acid binding IEA Interproscan
MF GO:0004812 aminoacyl-tRNA ligase activity IEA Interproscan
MF GO:0005524 ATP binding IEA Interproscan
BP GO:0006418 tRNA aminoacylation for protein translation IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR004364 Aa-tRNA-synt_II 229 551
IPR004365 NA-bd_OB_tRNA 109 196
No external refs found!