Description : Aspartyl-tRNA synthetase, primarily cytoplasmic; homodimeric enzyme that catalyzes the specific aspartylation of tRNA(Asp); class II aminoacyl tRNA synthetase; binding to its own mRNA may confer autoregulation; shares five highly conserved amino acids with human that when mutated cause leukoencephalopathy characterized by hypomyelination with brain stem and spinal cord involvement and leg spasticity (HBSL) [Source:SGD;Acc:S000003941]
Gene families : OG_03_0000561 (OF) Phylogenetic Tree(s): OG0000561_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YLL018C | |
Cluster | HCCA: Cluster_7 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR94626 | No alias | aspartate-tRNA(Asn) ligase;tRNA synthetases class II (D, K and N) | 0.02 | OF | |
AOA65984 | No alias | Aminoacyl-tRNA synthetase, class II (D/K/N) | 0.07 | OF | |
CAG81342 | No alias | Aminoacyl-tRNA synthetase, class II (D/K/N) | 0.03 | OF | |
CAK48970 | No alias | tRNA synthetases class II (D, K and N) | 0.13 | OF | |
CBF77275 | No alias | aspartyl-tRNA synthetase Dps1, putative | 0.06 | OF | |
EAL87356 | No alias | aspartyl-tRNA synthetase Dps1, putative | 0.13 | OF | |
EAU93029 | No alias | aspartate-tRNA ligase | 0.04 | OF | |
EDN93572 | No alias | Aminoacyl-tRNA synthetase, class II (D/K/N) | 0.08 | OF | |
EED77558 | No alias | OB-fold nucleic acid binding domain, AA-tRNA synthetase-type | 0.04 | OF | |
ESU08534 | No alias | Aminoacyl-tRNA synthetase, class II (D/K/N) | 0.02 | OF | |
KHC71277 | No alias | aspartyl-tRNA synthetase, cytoplasmic;OB-fold nucleic... | 0.05 | OF | |
MGG_12574T0 | No alias | Aspartyl-tRNA synthetase [Source:UniProtKB/TrEMBL;Acc:G4NLR3] | 0.04 | OF | |
POW12880 | No alias | Aminoacyl-tRNA synthetase, class II (D/K/N);OB-fold... | 0.04 | OF | |
SPCC1223.07c.1 | No alias | cytoplasmic aspartate-tRNA ligase Drs1 (predicted)... | 0.11 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0000166 | nucleotide binding | IEA | Interproscan |
MF | GO:0003676 | nucleic acid binding | IEA | Interproscan |
MF | GO:0004812 | aminoacyl-tRNA ligase activity | IEA | Interproscan |
MF | GO:0005524 | ATP binding | IEA | Interproscan |
BP | GO:0006418 | tRNA aminoacylation for protein translation | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |