YKR087C


Description : Metalloendopeptidase of the mitochondrial inner membrane; important for adaptive responses to various homeostatic insults, preservation of normal mitochondrial function under damage-eliciting conditions, and stability of respiratory supercomplexes; involved in turnover of membrane-embedded proteins; mediates degradation of Cox1p in coa2 mutant cells; zebrafish ortholog has a role in organ development and mouse ortholog is also required for respiratory supercomplex stability [Source:SGD;Acc:S000001795]


Gene families : OG_03_0001556 (OF) Phylogenetic Tree(s): OG0001556_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YKR087C
Cluster HCCA: Cluster_60


Type GO Term Name Evidence Source
MF GO:0004222 metalloendopeptidase activity IEA Interproscan
BP GO:0006508 proteolysis IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR001915 Peptidase_M48 157 319
No external refs found!