Description : Deoxyhypusine synthase; catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis; triggers posttranslational hypusination of translation elongation factor eIF-5A and regulates its intracellular levels; tetrameric; human homolog DHPS allows growth of yeast haploid dys1 null mutant after sporulation of heterozygous diploid [Source:SGD;Acc:S000001110]
Gene families : OG_03_0003209 (OF) Phylogenetic Tree(s): OG0003209_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YHR068W | |
Cluster | HCCA: Cluster_8 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AOA66897 | No alias | Deoxyhypusine synthase | 0.06 | OF | |
EAU84757 | No alias | deoxyhypusine synthase | 0.02 | OF | |
EDN97137 | No alias | Deoxyhypusine synthase | 0.03 | OF | |
ESU05487 | No alias | deoxyhypusine synthase | 0.02 | OF | |
KHC79745 | No alias | deoxyhypusine synthase;Deoxyhypusine synthase | 0.13 | OF | |
KHC80160 | No alias | deoxyhypusine synthase;Deoxyhypusine synthase | 0.13 | OF | |
SPBC1271.04c.1 | No alias | eIF-5A-deoxyhypusine synthase (predicted)... | 0.05 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR002773 | Deoxyhypusine_synthase | 47 | 375 |
No external refs found! |