Description : Methionyl-tRNA synthetase; forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs; mutations in human ortholog MARS are associated with pediatric pulmonary alveolar proteinosis [Source:SGD;Acc:S000003496]
Gene families : OG_03_0003447 (OF) Phylogenetic Tree(s): OG0003447_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YGR264C | |
Cluster | HCCA: Cluster_8 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR94837 | No alias | methionine-tRNA ligase;tRNA synthetases class I (M) | 0.06 | OF | |
CAG78837 | No alias | Methionyl/Leucyl tRNA synthetase | 0.08 | OF | |
CAK45203 | No alias | tRNA synthetases class I (M) | 0.1 | OF | |
CBF87610 | No alias | methionyl-tRNA synthetase | 0.14 | OF | |
EAA35402 | No alias | Methionyl/Leucyl tRNA synthetase | 0.11 | OF | |
EAL90230 | No alias | methionyl-tRNA synthetase | 0.12 | OF | |
EAU85609 | No alias | methionyl tRNA synthetase | 0.02 | OF | |
EED81599 | No alias | Methionyl/Leucyl tRNA synthetase | 0.03 | OF | |
EGR44409 | No alias | Methionyl/Leucyl tRNA synthetase | 0.08 | OF | |
ESU14708 | No alias | methionyl-tRNA synthetase | 0.1 | OF | |
KHC75362 | No alias | methionine-tRNA ligase;tRNA synthetases class I... | 0.13 | OF | |
MGG_01046T0 | No alias | Methionyl-tRNA synthetase [Source:UniProtKB/TrEMBL;Acc:G4NCR9] | 0.1 | OF | |
SPBC17A3.04c.1 | No alias | cytoplasmic methionine-tRNA ligase Mrs1 (predicted)... | 0.15 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0000166 | nucleotide binding | IEA | Interproscan |
MF | GO:0004812 | aminoacyl-tRNA ligase activity | IEA | Interproscan |
MF | GO:0005524 | ATP binding | IEA | Interproscan |
BP | GO:0006418 | tRNA aminoacylation for protein translation | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |