Description : Clathrin heavy chain; subunit of the major coat protein involved in intracellular protein transport and endocytosis; the clathrin triskelion is a trimeric molecule composed of three heavy chains that radiate from a vertex and three light chains which bind noncovalently near the vertex of the triskelion; the light chain (CLC1) is thought to regulate function [Source:SGD;Acc:S000003174]
Gene families : OG_03_0003110 (OF) Phylogenetic Tree(s): OG0003110_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YGL206C | |
| Cluster | HCCA: Cluster_8 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| AFR97311 | No alias | clathrin heavy chain;Clathrin, heavy-chain... | 0.08 | OF | |
| AOA66325 | No alias | Clathrin-H-link | 0.05 | OF | |
| CAG84082 | No alias | Clathrin-H-link | 0.1 | OF | |
| CAL00694 | No alias | Region in Clathrin and VPS | 0.06 | OF | |
| CBF77469 | No alias | clathrin heavy chain | 0.06 | OF | |
| EAA36405 | No alias | Clathrin-H-link | 0.08 | OF | |
| EAL90017 | No alias | clathrin heavy chain | 0.1 | OF | |
| EAU90123 | No alias | clathrin heavy chain 1 | 0.08 | OF | |
| EGR46240 | No alias | Clathrin, heavy chain, propeller repeat | 0.15 | OF | |
| ESU11605 | No alias | clathrin heavy chain | 0.1 | OF | |
| KHC73352 | No alias | clathrin heavy chain;Clathrin-H-link;Region in Clathrin... | 0.15 | OF | |
| MGG_07768T0 | No alias | Clathrin heavy chain [Source:UniProtKB/TrEMBL;Acc:G4N0Z8] | 0.08 | OF | |
| SPAC26A3.05.1 | No alias | clathrin heavy chain Chc1 (predicted)... | 0.09 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0005198 | structural molecule activity | IEA | Interproscan |
| BP | GO:0006886 | intracellular protein transport | IEA | Interproscan |
| BP | GO:0016192 | vesicle-mediated transport | IEA | Interproscan |
| CC | GO:0030130 | clathrin coat of trans-Golgi network vesicle | IEA | Interproscan |
| CC | GO:0030132 | clathrin coat of coated pit | IEA | Interproscan |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR015348 | Clathrin_H-chain_linker_core | 339 | 360 |
| IPR000547 | Clathrin_H-chain/VPS_repeat | 545 | 675 |
| IPR000547 | Clathrin_H-chain/VPS_repeat | 1280 | 1423 |
| IPR000547 | Clathrin_H-chain/VPS_repeat | 986 | 1124 |
| IPR000547 | Clathrin_H-chain/VPS_repeat | 694 | 832 |
| IPR000547 | Clathrin_H-chain/VPS_repeat | 840 | 968 |
| IPR000547 | Clathrin_H-chain/VPS_repeat | 1429 | 1569 |
| IPR000547 | Clathrin_H-chain/VPS_repeat | 1135 | 1273 |
| IPR022365 | Clathrin_H-chain_propeller_rpt | 151 | 189 |
| No external refs found! |