YER022W

Description : Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for basal RNA polymerase II transcription; homozygosity of the human MED17 L371P mutation is associated with infantile cerebral and cerebellar atrophy with poor myelination [Source:SGD;Acc:S000000824]

Gene families : OG_03_0004632 (OF) Phylogenetic Tree(s): OG0004632_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YER022W
Cluster	HCCA: Cluster_23

Target	Alias	Description	ECC score	Gene Family Method
AOA67037	No alias	Mediator complex, subunit Med17	0.07	OF
CAG78802	No alias	Mediator complex, subunit Med17	0.07	OF
EGR52521	No alias	Mediator complex, subunit Med17	0.03	OF
ESU14789	No alias	Mediator complex, subunit Med17	0.03	OF
KHC83133	No alias	hypothetical protein;Subunit 17 of Mediator complex	0.04	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003712	transcription coregulator activity	IEA	Interproscan
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006355	regulation of transcription, DNA-templated	None	Extended
BP	GO:0006357	regulation of transcription by RNA polymerase II	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
CC	GO:0016592	mediator complex	IEA	Interproscan
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051252	regulation of RNA metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
MF	GO:0140110	transcription regulator activity	None	Extended
BP	GO:1903506	regulation of nucleic acid-templated transcription	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended
BP	GO:2001141	regulation of RNA biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR019313	Mediator_Med17	13	568

External Links

No external refs found!

YER022W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation