1. Home
  2. GO
  3. GO:0003712

GO:0003712: transcription coregulator activity (Molecular function)

"A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to either activate or repress the transcription of specific genes. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class modulates interactions of DNA-binding transcription factor with other transcription coregulators." [GOC:txnOH-2018, PMID:10213677, PMID:16858867, PMID:24203923, PMID:25957681, Wikipedia:Transcription_coregulator]


There are 346 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_48 Saccharomyces cerevisiae 3.45 % 0.004126 0.030031
Cluster_44 Aspergillus niger 1.47 % 0.01449 0.041934
Cluster_74 Candida albicans 33.33 % 0.011689 0.048949
Cluster_50 Candida albicans 5.06 % 0.000224 0.021025
Cluster_36 Fusarium graminearum 5.8 % 2e-06 0.000155
Cluster_41 Neurospora crassa 3.03 % 0.000108 0.007309
Cluster_18 Neurospora crassa 1.56 % 0.005799 0.030574
Cluster_17 Neurospora crassa 2.05 % 0.002687 0.020905
Cluster_81 Neurospora crassa 3.7 % 0.004842 0.018627
Cluster_31 Puccinia striiformis 1.28 % 0.017859 0.046851
Cluster_16 Trichoderma reesei 1.48 % 0.008106 0.042015
Cluster_74 Sclerotinia sclerotiorum 2.24 % 0.000731 0.007408
Sequences (346) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms