1. Home
  2. Species
  3. Saccharomyces cerevisiae
  4. Sequence
  5. YEL071W

YEL071W


Description : 2-hydroxyglutarate transhydrogenase, and minor D-lactate dehydrogenase; converts D-2-hydroxyglutarate (D-2HG), an oncometabolite, to alpha-ketoglutarate in the presence of FAD, with concomitant reduction of pyruvate to D-lactate; minor lactate dehydrogenase activity; component of the retrograde regulon that consists of genes whose expression are stimulated by damage to mitochondria and reduced in cells grown with glutamate as the sole nitrogen source; located in the cytoplasm [Source:SGD;Acc:S000000797]


Gene families : OG_03_0002340 (OF) Phylogenetic Tree(s): OG0002340_tree

Sequence : coding (download), protein (download)


Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YEL071W
Cluster HCCA: Cluster_7

Target Alias Description ECC score Gene Family Method Actions
AFR94027 No alias D-lactate dehydrogenase;FAD linked oxidases, C-terminal... 0.02 OF
AOA68513 No alias FAD linked oxidase, N-terminal 0.03 OF
CAG81820 No alias FAD linked oxidase, N-terminal 0.09 OF
CBF73743 No alias actin interacting protein 2 0.03 OF
EAA28096 No alias FAD linked oxidase, N-terminal 0.02 OF
EAU92870 No alias D2HGD protein 0.02 OF
KHC78855 No alias hypothetical protein;FAD binding domain;"FAD linked... 0.06 OF

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA Interproscan
MF GO:0016491 oxidoreductase activity IEA Interproscan
MF GO:0050660 flavin adenine dinucleotide binding IEA Interproscan
BP GO:0055114 oxidation-reduction process IEA Interproscan
Toggle parental
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR006094 Oxid_FAD_bind_N 70 204
IPR004113 FAD-linked_oxidase_C 243 494
No external refs found!