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Expression profile for YEL071W (YEL071W)

Description : 2-hydroxyglutarate transhydrogenase, and minor D-lactate dehydrogenase; converts D-2-hydroxyglutarate (D-2HG), an oncometabolite, to alpha-ketoglutarate in the presence of FAD, with concomitant reduction of pyruvate to D-lactate; minor lactate dehydrogenase activity; component of the retrograde regulon that consists of genes whose expression are stimulated by damage to mitochondria and reduced in cells grown with glutamate as the sole nitrogen source; located in the cytoplasm [Source:SGD;Acc:S000000797]

Sample enrichment: rap,YPD,WT (SPM: 0.37, entropy: 3.5, tau: 0.75)
Perturbation specificity: Rapamycin (SPM: 0.58, entropy: 3.25, tau: 0.68)