YAR008W

Description : Subunit of the tRNA splicing endonuclease; tRNA splicing endonuclease (Sen complex) is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen complex also cleaves the CBP1 mRNA at the mitochondrial surface; Sen34p contains the active site for tRNA 3' splice site cleavage and has similarity to Sen2p and to Archaeal tRNA splicing endonuclease [Source:SGD;Acc:S000000066]

Gene families : OG_03_0002113 (OF) Phylogenetic Tree(s): OG0002113_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YAR008W
Cluster	HCCA: Cluster_58

Target	Alias	Description	ECC score	Gene Family Method	Actions
AOA66995	No alias	tRNA intron endonuclease, catalytic domain-like	0.03	OF
KHC81608	No alias	tRNA-intron endonuclease;"tRNA intron endonuclease,...	0.03	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000213	tRNA-intron endonuclease activity	IEA	Interproscan
BP	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004519	endonuclease activity	None	Extended
MF	GO:0004521	endoribonuclease activity	None	Extended
MF	GO:0004540	ribonuclease activity	None	Extended
MF	GO:0004549	tRNA-specific ribonuclease activity	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	IEA	Interproscan
BP	GO:0006396	RNA processing	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008033	tRNA processing	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008380	RNA splicing	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters	None	Extended
MF	GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	None	Extended
BP	GO:0034470	ncRNA processing	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR006677	tRNA_intron_Endonuc_cat-like	183	262

External Links

No external refs found!

YAR008W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation