Coexpression cluster: Cluster_27 (HCCA)

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:0003676 nucleic acid binding 23.17% (19/82) 2.36 0.0 1e-06
GO:0006260 DNA replication 6.1% (5/82) 5.82 0.0 1e-06
GO:0006259 DNA metabolic process 9.76% (8/82) 4.15 0.0 2e-06
GO:1901363 heterocyclic compound binding 30.49% (25/82) 1.68 0.0 4e-06
GO:0097159 organic cyclic compound binding 30.49% (25/82) 1.68 0.0 4e-06
GO:0005488 binding 35.37% (29/82) 1.33 1e-06 3.3e-05
GO:0003677 DNA binding 13.41% (11/82) 2.71 1e-06 3.5e-05
GO:0032991 protein-containing complex 12.2% (10/82) 2.87 1e-06 3.6e-05
GO:0006270 DNA replication initiation 3.66% (3/82) 6.54 2e-06 5.7e-05
GO:0000786 nucleosome 3.66% (3/82) 5.96 1e-05 0.00018
GO:0032993 protein-DNA complex 3.66% (3/82) 5.96 1e-05 0.00018
GO:0044815 DNA packaging complex 3.66% (3/82) 5.96 1e-05 0.00018
GO:0005575 cellular_component 23.17% (19/82) 1.62 8e-06 0.000189
GO:0044260 cellular macromolecule metabolic process 15.85% (13/82) 2.11 8e-06 0.000206
GO:0044237 cellular metabolic process 20.73% (17/82) 1.7 1.3e-05 0.000214
GO:0032555 purine ribonucleotide binding 14.63% (12/82) 2.11 1.9e-05 0.000271
GO:0003674 molecular_function 47.56% (39/82) 0.88 1.8e-05 0.000272
GO:0035639 purine ribonucleoside triphosphate binding 14.63% (12/82) 2.12 1.8e-05 0.000279
GO:0017076 purine nucleotide binding 14.63% (12/82) 2.09 2.2e-05 0.000288
GO:0032553 ribonucleotide binding 14.63% (12/82) 2.06 2.7e-05 0.000342
GO:1901360 organic cyclic compound metabolic process 13.41% (11/82) 2.16 3.1e-05 0.000373
GO:0097367 carbohydrate derivative binding 14.63% (12/82) 2.02 3.3e-05 0.000386
GO:0006139 nucleobase-containing compound metabolic process 12.2% (10/82) 2.23 5e-05 0.000549
GO:0006269 DNA replication, synthesis of RNA primer 2.44% (2/82) 6.96 6.4e-05 0.000652
GO:0043170 macromolecule metabolic process 17.07% (14/82) 1.74 6.2e-05 0.000653
GO:0071704 organic substance metabolic process 21.95% (18/82) 1.44 7.4e-05 0.000725
GO:0090304 nucleic acid metabolic process 10.98% (9/82) 2.29 8.6e-05 0.00081
GO:0005524 ATP binding 12.2% (10/82) 2.12 9.1e-05 0.00083
GO:0046483 heterocycle metabolic process 12.2% (10/82) 2.09 0.000109 0.000863
GO:0006725 cellular aromatic compound metabolic process 12.2% (10/82) 2.1 0.000106 0.000866
GO:0030554 adenyl nucleotide binding 12.2% (10/82) 2.1 0.000106 0.000866
GO:0032559 adenyl ribonucleotide binding 12.2% (10/82) 2.11 0.0001 0.000874
GO:0140097 catalytic activity, acting on DNA 3.66% (3/82) 4.73 0.000172 0.001326
GO:0009058 biosynthetic process 12.2% (10/82) 2.0 0.000183 0.001364
GO:0005643 nuclear pore 2.44% (2/82) 6.37 0.000191 0.00139
GO:0008144 drug binding 12.2% (10/82) 1.96 0.00023 0.001624
GO:0044249 cellular biosynthetic process 10.98% (9/82) 2.06 0.000283 0.001944
GO:0000166 nucleotide binding 14.63% (12/82) 1.69 0.000311 0.002025
GO:1901265 nucleoside phosphate binding 14.63% (12/82) 1.69 0.000311 0.002025
GO:1901576 organic substance biosynthetic process 10.98% (9/82) 2.04 0.000325 0.002062
GO:0043168 anion binding 14.63% (12/82) 1.62 0.000473 0.002863
GO:0009059 macromolecule biosynthetic process 8.54% (7/82) 2.33 0.000473 0.002933
GO:0036094 small molecule binding 14.63% (12/82) 1.59 0.000548 0.003238
GO:0034641 cellular nitrogen compound metabolic process 12.2% (10/82) 1.74 0.000774 0.004466
GO:0003678 DNA helicase activity 2.44% (2/82) 5.37 0.000942 0.005319
GO:0008152 metabolic process 24.39% (20/82) 1.04 0.001163 0.006422
GO:0009987 cellular process 23.17% (19/82) 1.04 0.001547 0.008359
GO:0008094 DNA-dependent ATPase activity 2.44% (2/82) 4.96 0.001741 0.009212
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 6.1% (5/82) 2.41 0.002489 0.012901
GO:0016817 hydrolase activity, acting on acid anhydrides 6.1% (5/82) 2.38 0.002679 0.013611
GO:0043167 ion binding 17.07% (14/82) 1.19 0.00286 0.014244
GO:0044238 primary metabolic process 17.07% (14/82) 1.19 0.002929 0.014309
GO:0006281 DNA repair 3.66% (3/82) 3.33 0.003218 0.01542
GO:0006974 cellular response to DNA damage stimulus 3.66% (3/82) 3.22 0.004021 0.018914
GO:0033554 cellular response to stress 3.66% (3/82) 3.18 0.004314 0.019565
GO:0110165 cellular anatomical entity 14.63% (12/82) 1.25 0.004273 0.019733
GO:0031224 intrinsic component of membrane 7.32% (6/82) 1.94 0.004688 0.020181
GO:0016021 integral component of membrane 7.32% (6/82) 1.94 0.004688 0.020181
GO:0051716 cellular response to stimulus 3.66% (3/82) 3.15 0.004619 0.020581
GO:1901615 organic hydroxy compound metabolic process 2.44% (2/82) 3.87 0.008067 0.022767
GO:0031511 Mis6-Sim4 complex 1.22% (1/82) 6.96 0.008059 0.023
GO:0071826 ribonucleoprotein complex subunit organization 1.22% (1/82) 6.96 0.008059 0.023
GO:0016093 polyprenol metabolic process 1.22% (1/82) 6.96 0.008059 0.023
GO:0042575 DNA polymerase complex 1.22% (1/82) 6.96 0.008059 0.023
GO:0043625 delta DNA polymerase complex 1.22% (1/82) 6.96 0.008059 0.023
GO:0009262 deoxyribonucleotide metabolic process 1.22% (1/82) 6.96 0.008059 0.023
GO:0004520 endodeoxyribonuclease activity 1.22% (1/82) 6.96 0.008059 0.023
GO:0032780 negative regulation of ATPase activity 1.22% (1/82) 6.96 0.008059 0.023
GO:0009263 deoxyribonucleotide biosynthetic process 1.22% (1/82) 6.96 0.008059 0.023
GO:0022618 ribonucleoprotein complex assembly 1.22% (1/82) 6.96 0.008059 0.023
GO:0003896 DNA primase activity 1.22% (1/82) 6.96 0.008059 0.023
GO:0000350 generation of catalytic spliceosome for second transesterification step 1.22% (1/82) 6.96 0.008059 0.023
GO:1905462 regulation of DNA duplex unwinding 1.22% (1/82) 6.96 0.008059 0.023
GO:0051095 regulation of helicase activity 1.22% (1/82) 6.96 0.008059 0.023
GO:0051097 negative regulation of helicase activity 1.22% (1/82) 6.96 0.008059 0.023
GO:0017108 5'-flap endonuclease activity 1.22% (1/82) 6.96 0.008059 0.023
GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1.22% (1/82) 6.96 0.008059 0.023
GO:0048256 flap endonuclease activity 1.22% (1/82) 6.96 0.008059 0.023
GO:0033557 Slx1-Slx4 complex 1.22% (1/82) 6.96 0.008059 0.023
GO:0042555 MCM complex 1.22% (1/82) 6.96 0.008059 0.023
GO:0043462 regulation of ATPase activity 1.22% (1/82) 6.96 0.008059 0.023
GO:0019348 dolichol metabolic process 1.22% (1/82) 6.96 0.008059 0.023
GO:1905463 negative regulation of DNA duplex unwinding 1.22% (1/82) 6.96 0.008059 0.023
GO:1905774 regulation of DNA helicase activity 1.22% (1/82) 6.96 0.008059 0.023
GO:1905775 negative regulation of DNA helicase activity 1.22% (1/82) 6.96 0.008059 0.023
GO:2001251 negative regulation of chromosome organization 1.22% (1/82) 6.96 0.008059 0.023
GO:0004386 helicase activity 2.44% (2/82) 4.15 0.005483 0.023211
GO:0006950 response to stress 3.66% (3/82) 3.05 0.005611 0.023364
GO:0034645 cellular macromolecule biosynthetic process 6.1% (5/82) 1.98 0.00863 0.024088
GO:0006807 nitrogen compound metabolic process 13.41% (11/82) 1.15 0.009815 0.027097
GO:0050896 response to stimulus 3.66% (3/82) 2.96 0.006722 0.027539
GO:0005634 nucleus 4.88% (4/82) 2.37 0.007426 0.02994
GO:0017111 nucleoside-triphosphatase activity 4.88% (4/82) 2.16 0.01223 0.033402
GO:0016462 pyrophosphatase activity 4.88% (4/82) 2.11 0.013782 0.037239
GO:0060249 anatomical structure homeostasis 1.22% (1/82) 5.96 0.016054 0.037756
GO:0000723 telomere maintenance 1.22% (1/82) 5.96 0.016054 0.037756
GO:0004536 deoxyribonuclease activity 1.22% (1/82) 5.96 0.016054 0.037756
GO:0032200 telomere organization 1.22% (1/82) 5.96 0.016054 0.037756
GO:0043086 negative regulation of catalytic activity 1.22% (1/82) 5.96 0.016054 0.037756
GO:0044092 negative regulation of molecular function 1.22% (1/82) 5.96 0.016054 0.037756
GO:0010639 negative regulation of organelle organization 1.22% (1/82) 5.96 0.016054 0.037756
GO:0051346 negative regulation of hydrolase activity 1.22% (1/82) 5.96 0.016054 0.037756
GO:0005664 nuclear origin of replication recognition complex 1.22% (1/82) 5.96 0.016054 0.037756
GO:0051129 negative regulation of cellular component organization 1.22% (1/82) 5.96 0.016054 0.037756
GO:0033044 regulation of chromosome organization 1.22% (1/82) 5.96 0.016054 0.037756
GO:0043231 intracellular membrane-bounded organelle 4.88% (4/82) 2.08 0.014602 0.038635
GO:0043227 membrane-bounded organelle 4.88% (4/82) 2.08 0.014602 0.038635
GO:0008150 biological_process 28.05% (23/82) 0.65 0.015598 0.040844
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
Saccharomyces cerevisiae HCCA Cluster_13 0.024 OF Compare
Saccharomyces cerevisiae HCCA Cluster_15 0.035 OF Compare
Saccharomyces cerevisiae HCCA Cluster_37 0.022 OF Compare
Saccharomyces cerevisiae HCCA Cluster_41 0.023 OF Compare
Saccharomyces cerevisiae HCCA Cluster_53 0.021 OF Compare
Saccharomyces cerevisiae HCCA Cluster_58 0.018 OF Compare
Saccharomyces cerevisiae HCCA Cluster_59 0.031 OF Compare
Saccharomyces cerevisiae HCCA Cluster_67 0.021 OF Compare
Aspergillus flavus HCCA Cluster_4 0.042 OF Compare
Aspergillus fumigatus HCCA Cluster_24 0.047 OF Compare
Aspergillus fumigatus HCCA Cluster_39 0.034 OF Compare
Aspergillus fumigatus HCCA Cluster_41 0.018 OF Compare
Aspergillus fumigatus HCCA Cluster_51 0.029 OF Compare
Aspergillus nidulans HCCA Cluster_18 0.065 OF Compare
Aspergillus nidulans HCCA Cluster_49 0.022 OF Compare
Aspergillus nidulans HCCA Cluster_54 0.017 OF Compare
Aspergillus nidulans HCCA Cluster_68 0.043 OF Compare
Aspergillus nidulans HCCA Cluster_74 0.021 OF Compare
Aspergillus nidulans HCCA Cluster_81 0.022 OF Compare
Aspergillus nidulans HCCA Cluster_97 0.028 OF Compare
Aspergillus niger HCCA Cluster_20 0.043 OF Compare
Aspergillus niger HCCA Cluster_26 0.048 OF Compare
Aspergillus niger HCCA Cluster_32 0.031 OF Compare
Aspergillus niger HCCA Cluster_58 0.022 OF Compare
Aspergillus niger HCCA Cluster_71 0.022 OF Compare
Aspergillus niger HCCA Cluster_89 0.044 OF Compare
Candida albicans HCCA Cluster_1 0.048 OF Compare
Candida albicans HCCA Cluster_19 0.019 OF Compare
Candida albicans HCCA Cluster_25 0.018 OF Compare
Candida albicans HCCA Cluster_38 0.035 OF Compare
Candida albicans HCCA Cluster_42 0.025 OF Compare
Candida albicans HCCA Cluster_49 0.022 OF Compare
Candida albicans HCCA Cluster_68 0.043 OF Compare
Coprinopsis cinerea HCCA Cluster_20 0.018 OF Compare
Coprinopsis cinerea HCCA Cluster_83 0.034 OF Compare
Coprinopsis cinerea HCCA Cluster_103 0.021 OF Compare
Coprinopsis cinerea HCCA Cluster_137 0.041 OF Compare
Cryptococcus neoformans HCCA Cluster_1 0.018 OF Compare
Cryptococcus neoformans HCCA Cluster_21 0.044 OF Compare
Cryptococcus neoformans HCCA Cluster_25 0.044 OF Compare
Cryptococcus neoformans HCCA Cluster_56 0.017 OF Compare
Cryptococcus neoformans HCCA Cluster_70 0.031 OF Compare
Dichomitus squalens HCCA Cluster_9 0.023 OF Compare
Dichomitus squalens HCCA Cluster_24 0.021 OF Compare
Dichomitus squalens HCCA Cluster_35 0.019 OF Compare
Fusarium graminearum HCCA Cluster_10 0.049 OF Compare
Fusarium graminearum HCCA Cluster_39 0.028 OF Compare
Fusarium graminearum HCCA Cluster_48 0.032 OF Compare
Fusarium graminearum HCCA Cluster_99 0.092 OF Compare
Komagataella phaffii HCCA Cluster_22 0.06 OF Compare
Komagataella phaffii HCCA Cluster_31 0.046 OF Compare
Komagataella phaffii HCCA Cluster_41 0.019 OF Compare
Komagataella phaffii HCCA Cluster_47 0.021 OF Compare
Neurospora crassa HCCA Cluster_7 0.022 OF Compare
Neurospora crassa HCCA Cluster_22 0.023 OF Compare
Neurospora crassa HCCA Cluster_29 0.14 OF Compare
Neurospora crassa HCCA Cluster_65 0.028 OF Compare
Postia placenta HCCA Cluster_57 0.02 OF Compare
Postia placenta HCCA Cluster_65 0.029 OF Compare
Puccinia striiformis HCCA Cluster_2 0.024 OF Compare
Puccinia striiformis HCCA Cluster_26 0.024 OF Compare
Puccinia striiformis HCCA Cluster_31 0.022 OF Compare
Pyricularia oryzae HCCA Cluster_10 0.049 OF Compare
Pyricularia oryzae HCCA Cluster_49 0.018 OF Compare
Pyricularia oryzae HCCA Cluster_73 0.031 OF Compare
Yarrowia lipolytica HCCA Cluster_5 0.018 OF Compare
Yarrowia lipolytica HCCA Cluster_12 0.069 OF Compare
Yarrowia lipolytica HCCA Cluster_16 0.03 OF Compare
Yarrowia lipolytica HCCA Cluster_25 0.02 OF Compare
Yarrowia lipolytica HCCA Cluster_45 0.031 OF Compare
Yarrowia lipolytica HCCA Cluster_51 0.018 OF Compare
Yarrowia lipolytica HCCA Cluster_57 0.024 OF Compare
Yarrowia lipolytica HCCA Cluster_58 0.031 OF Compare
Schizosaccharomyces pombe HCCA Cluster_3 0.02 OF Compare
Schizosaccharomyces pombe HCCA Cluster_14 0.02 OF Compare
Schizosaccharomyces pombe HCCA Cluster_18 0.018 OF Compare
Schizosaccharomyces pombe HCCA Cluster_27 0.018 OF Compare
Schizosaccharomyces pombe HCCA Cluster_28 0.021 OF Compare
Schizosaccharomyces pombe HCCA Cluster_29 0.02 OF Compare
Schizosaccharomyces pombe HCCA Cluster_38 0.022 OF Compare
Schizosaccharomyces pombe HCCA Cluster_40 0.022 OF Compare
Schizosaccharomyces pombe HCCA Cluster_41 0.02 OF Compare
Schizosaccharomyces pombe HCCA Cluster_53 0.03 OF Compare
Trichoderma reesei HCCA Cluster_2 0.026 OF Compare
Trichoderma reesei HCCA Cluster_16 0.04 OF Compare
Trichoderma reesei HCCA Cluster_19 0.034 OF Compare
Trichoderma reesei HCCA Cluster_70 0.022 OF Compare
Sequences (82) (download table)

InterPro Domains

GO Terms

Family Terms