Description : Component of the heterotetrameric MHF histone-fold complex; in humans the MHF complex interacts with both DNA and Mph1p ortholog FANCM to stabilize and remodel blocked replication forks and repair damaged DNA; mhf2 srs2 double mutants are MMS hypersensitive; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-X, also known as MHF2 [Source:SGD;Acc:S000028520]
Gene families : OG_03_0005441 (OF) Phylogenetic Tree(s): OG0005441_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YDL160C-A | |
Cluster | HCCA: Cluster_67 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0006281 | DNA repair | IEA | Interproscan |
BP | GO:0051382 | kinetochore assembly | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR018552 | CENP-X | 5 | 80 |
No external refs found! |