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  5. YDL074C

YDL074C


Description : E3 ubiquitin ligase; forms heterodimer with Rad6p to regulate K63 polyubiquitination in response to oxidative stress and to monoubiquinate histone H2B-K123, which is required for the subsequent methylation of histone H3-K4 and H3-K79; required for DSBR, transcription, silencing, and checkpoint control; interacts with RNA-binding protein Npl3p, linking histone ubiquitination to mRNA processing; Bre1p-dependent histone ubiquitination promotes pre-mRNA splicing [Source:SGD;Acc:S000002232]


Gene families : OG_03_0001068 (OF) Phylogenetic Tree(s): OG0001068_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YDL074C
Cluster HCCA: Cluster_63

Target Alias Description ECC score Gene Family Method Actions
AFR97034 No alias E3 ubiquitin-protein ligase BRE1;Zinc finger, C3HC4 type... 0.03 OF
AOA69605 No alias BRE1 E3 ubiquitin ligase 0.08 OF
CAG82928 No alias Zinc finger, C3HC4 type (RING finger) 0.04 OF
CAK42265 No alias Zinc finger, C3HC4 type (RING finger) 0.02 OF
CBF71013 No alias histone ubiquitinationc protein 0.03 OF
EAL85601 No alias histone ubiquitinationc protein (Bre1), putative 0.06 OF
EAU91038 No alias BRE1 E3 ubiquitin ligase 0.03 OF
EED84522 No alias Zinc finger, C3HC4 RING-type 0.04 OF
ESU12911 No alias ubiquitin-protein ligase BRE1 0.04 OF
KHC74935 No alias E3 ubiquitin-protein ligase BRE1;BRE1 E3 ubiquitin... 0.03 OF
SPCC970.10c.1 No alias ubiquitin-protein ligase E3 Brl2 [Source:PomBase;Acc:SPCC970.10c] 0.06 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

No InterPro domains available for this sequence

No external refs found!