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Expression profile for YDL074C (YDL074C)

Description : E3 ubiquitin ligase; forms heterodimer with Rad6p to regulate K63 polyubiquitination in response to oxidative stress and to monoubiquinate histone H2B-K123, which is required for the subsequent methylation of histone H3-K4 and H3-K79; required for DSBR, transcription, silencing, and checkpoint control; interacts with RNA-binding protein Npl3p, linking histone ubiquitination to mRNA processing; Bre1p-dependent histone ubiquitination promotes pre-mRNA splicing [Source:SGD;Acc:S000002232]

Sample enrichment: dmso,WT (SPM: 0.3, entropy: 3.88, tau: 0.61)
Perturbation specificity: Glu (SPM: 0.62, entropy: 2.86, tau: 0.64)

All conditions


Perturbation specificity

Note: SPM calculations for this profile are done using the maximum value.