AFR96434

Description : multidomain RhoGEF;Pleckstrin homology domain;WH2 motif;SH3 domain;Domain of unknown function (DUF1720);Cytoskeletal-regulatory complex EF hand;RhoGEF domain

Gene families : OG_03_0002107 (OF) Phylogenetic Tree(s): OG0002107_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AFR96434
Cluster	HCCA: Cluster_77

Target	Alias	Description	ECC score	Gene Family Method
AOA68617	No alias	Domain of unknown function DUF1720	0.04	OF
CAG81042	No alias	EH domain	0.03	OF
CAK46430	No alias	Domain of unknown function (DUF1720)	0.02	OF
CBF74351	No alias	Actin cytoskeleton-regulatory complex protein pan1	0.11	OF
EAA33504	No alias	EH domain	0.06	OF
EAL87083	No alias	actin cortical patch assembly protein Pan1, putative	0.02	OF
EAU81913	No alias	Dbl homology (DH) domainSH3 domainSH3 domainEH...	0.06	OF
EDO03506	No alias	EH domain	0.04	OF
EGR52784	No alias	WH2 domain	0.08	OF
EJF56295	No alias	Variant SH3 domain	0.04	OF
ESU13109	No alias	EH domain	0.13	OF
KHC81398	No alias	actin cytoskeleton-regulatory complex protein...	0.03	OF
POW14978	No alias	Pleckstrin homology domain;Dbl homology (DH) domain	0.02	OF
SPAC25G10.09c.1	No alias	actin cortical patch component, with EF hand and WH2...	0.03	OF
YIR006C	No alias	Part of actin cytoskeleton-regulatory complex...	0.04	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003779	actin binding	IEA	Interproscan
MF	GO:0005085	guanyl-nucleotide exchange factor activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IEA	Interproscan
MF	GO:0008092	cytoskeletal protein binding	None	Extended
MF	GO:0019899	enzyme binding	None	Extended
MF	GO:0051020	GTPase binding	None	Extended
MF	GO:0098772	molecular function regulator	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR001849	PH_domain	1823	1933
IPR003124	WH2_dom	943	969
IPR001452	SH3_domain	1097	1146
IPR001452	SH3_domain	1158	1196
IPR013182	DUF1720	109	168
IPR000261	EH_dom	226	319
IPR000219	DH-domain	1617	1792

External Links

No external refs found!

AFR96434

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation