Description : Forkhead transcription factor; drives S-phase activation of genes involved in chromosome segregation, spindle dynamics, budding; also activates genes involved in respiration, use of alternative energy sources (like proline), NAD synthesis, oxidative stress resistance; key factor in early adaptation to nutrient deficiency and diauxic shift; suppressor of calmodulin mutants with specific SPB assembly defects; ortholog of C. elegans lifespan regulator PHA-4 [Source:SGD;Acc:S000000661]
Gene families : OG_03_0000190 (OF) Phylogenetic Tree(s): OG0000190_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YCR065W | |
Cluster | HCCA: Cluster_11 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR94127 | No alias | hepatocyte nuclear factor;Forkhead domain | 0.07 | OF | |
AFR96341 | No alias | forkhead transcription factor 3;Forkhead domain | 0.03 | OF | |
AFR96437 | No alias | forkhead domain-containing protein;Forkhead domain | 0.02 | OF | |
AFR98961 | No alias | hypothetical protein;Forkhead domain;FHA domain | 0.03 | OF | |
AOA65833 | No alias | Fork head domain | 0.03 | OF | |
CAG81933 | No alias | Forkhead-associated (FHA) domain | 0.03 | OF | |
EDN91177 | No alias | Fork head domain | 0.02 | OF | |
EGR52782 | No alias | Fork head domain | 0.02 | OF | |
ESA43188 | No alias | Fork head domain | 0.03 | OF | |
KHC83733 | No alias | forkhead transcription factor HCM1;Forkhead domain | 0.03 | OF | |
POV96975 | No alias | Fork head domain | 0.02 | OF | |
POW01842 | No alias | Forkhead-associated (FHA) domain;Fork head domain | 0.02 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003700 | DNA-binding transcription factor activity | IEA | Interproscan |
BP | GO:0006355 | regulation of transcription, DNA-templated | IEA | Interproscan |
MF | GO:0043565 | sequence-specific DNA binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR001766 | Fork_head_dom | 108 | 191 |
No external refs found! |