Description : Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex; which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity; null mutation is functionally complemented by human ELP4 [Source:SGD;Acc:S000006022]
Gene families : OG_03_0002094 (OF) Phylogenetic Tree(s): OG0002094_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YPL101W | |
| Cluster | HCCA: Cluster_13 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| CAG78537 | No alias | Elongator complex protein 4 | 0.03 | OF | |
| CAK43591 | No alias | PAXNEB protein | 0.02 | OF | |
| CBF90005 | No alias | PAXNEB protein superfamily | 0.03 | OF | |
| ESU08845 | No alias | Elongator complex protein 4 | 0.03 | OF | |
| KHC83993 | No alias | elongator complex protein 4;PAXNEB protein | 0.03 | OF | |
| POW12015 | No alias | Elongator complex protein 4 | 0.03 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| BP | GO:0002098 | tRNA wobble uridine modification | IEA | Interproscan |
| CC | GO:0033588 | Elongator holoenzyme complex | IEA | Interproscan |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR008728 | Elongator_complex_protein_4 | 71 | 438 |
| No external refs found! |