Description : Cytosolic and mitochondrial glutathione oxidoreductase; converts oxidized glutathione to reduced glutathione; cytosolic Glr1p is the main determinant of the glutathione redox state of the mitochondrial intermembrane space; mitochondrial Glr1p has a role in resistance to hyperoxia; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000006012]

Gene families : OG_03_0002617 (OF) Phylogenetic Tree(s): OG0002617_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YPL091W
Cluster HCCA: Cluster_19

Target Alias Description ECC score Gene Family Method Actions
AFR95434 No alias glutathione-disulfide reductase;Pyridine... 0.03 OF
CAG79681 No alias Pyridine nucleotide-disulphide oxidoreductase,... 0.02 OF
CAK47805 No alias Pyridine nucleotide-disulphide oxidoreductase 0.07 OF
EGR52340 No alias Pyridine nucleotide-disulphide oxidoreductase,... 0.05 OF
ESA43520 No alias FAD/NAD(P)-binding domain 0.03 OF
ESA43521 No alias FAD/NAD(P)-binding domain 0.03 OF
ESU11113 No alias glutathione reductase 0.06 OF
KHC75056 No alias glutathione reductase;Pyridine nucleotide-disulphide... 0.07 OF
MGG_12749T0 No alias Glutathione reductase [Source:UniProtKB/TrEMBL;Acc:G4N9X2] 0.02 OF
SPBC17A3.07.1 No alias mitochondrial glutathione reductase Pgr1... 0.04 OF

Type GO Term Name Evidence Source
MF GO:0016491 oxidoreductase activity IEA Interproscan
BP GO:0045454 cell redox homeostasis IEA Interproscan
BP GO:0055114 oxidation-reduction process IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR023753 FAD/NAD-binding_dom 24 349
IPR004099 Pyr_nucl-diS_OxRdtase_dimer 372 482
No external refs found!