Description : Mitochondrial DNA polymerase gamma; single subunit of mitochondrial DNA polymerase in yeast, in contrast to metazoan complex of catalytic and accessory subunits; polymorphic in yeast, petites occur more frequently in some lab strains; human ortholog POLG complements yeast mip1 mutant; mutations in human POLG associated with Alpers-Huttenlocher syndrome (AHS), progressive external ophthalmoplegia (PEO), parkinsonism, other mitochondrial diseases [Source:SGD;Acc:S000005857]
Gene families : OG_03_0003235 (OF) Phylogenetic Tree(s): OG0003235_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YOR330C | |
Cluster | HCCA: Cluster_48 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR93032 | No alias | DNA polymerase gamma 1;DNA mitochondrial polymerase... | 0.05 | OF | |
CAG78428 | No alias | DNA mitochondrial polymerase, exonuclease domain | 0.04 | OF | |
CAK97229 | No alias | DNA mitochondrial polymerase exonuclease domain | 0.01 | OF | |
CBF90322 | No alias | DNA polymerase gamma | 0.07 | OF | |
EAL91351 | No alias | DNA polymerase gamma | 0.05 | OF | |
KHC73869 | No alias | DNA polymerase gamma 1;DNA mitochondrial polymerase... | 0.05 | OF | |
MGG_08913T0 | No alias | DNA polymerase gamma [Source:UniProtKB/TrEMBL;Acc:G4MVM6] | 0.04 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003677 | DNA binding | IEA | Interproscan |
MF | GO:0003887 | DNA-directed DNA polymerase activity | IEA | Interproscan |
BP | GO:0006260 | DNA replication | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |