YOR244W


Description : Catalytic subunit of the histone acetyltransferase complex (NuA4); acetylates four conserved internal lysines of histone H4 N-terminal tail and can acetylate histone H2A; master regulator of cellular acetylation balance; required for cell cycle progression and transcriptional silencing at the rDNA locus and regulation of autophagy; human ortholog TIP60/KAT5 is implicated in cancer and other diseases, functionally complements lethality of the esa1 null mutation [Source:SGD;Acc:S000005770]


Gene families : OG_03_0000399 (OF) Phylogenetic Tree(s): OG0000399_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YOR244W
Cluster HCCA: Cluster_68

Target Alias Description ECC score Gene Family Method Actions
EAL89699 No alias histone acetyltransferase, putative 0.02 OF
ESU08867 No alias histone acetyltransferase E 0.03 OF
MGG_04133T0 No alias Histone acetyltransferase esa-1... 0.03 OF

Type GO Term Name Evidence Source
MF GO:0004402 histone acetyltransferase activity IEA Interproscan
BP GO:0006355 regulation of transcription, DNA-templated IEA Interproscan
BP GO:0016573 histone acetylation IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR025995 Tudor-knot 22 74
IPR040706 Zf-MYST 164 218
IPR002717 HAT_MYST-type 223 400
No external refs found!