YOR217W

Description : Subunit of heteropentameric Replication factor C (RF-C); RF-C is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon [Source:SGD;Acc:S000005743]

Gene families : OG_03_0001644 (OF) Phylogenetic Tree(s): OG0001644_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YOR217W
Cluster	HCCA: Cluster_59

Target	Alias	Description	ECC score	Gene Family Method
AFR94048	No alias	replication factor C subunit 1;BRCA1 C Terminus (BRCT)...	0.02	OF
AOA66518	No alias	BRCT domain	0.08	OF
CAG83248	No alias	BRCT domain	0.11	OF
CAK37567	No alias	Replication factor RFC1 C terminal domain	0.04	OF
CBF69746	No alias	Replication factor C like protein	0.07	OF
EAA34303	No alias	BRCT domain	0.06	OF
EAL93516	No alias	DNA replication factor C subunit Rfc1, putative	0.02	OF
EAU82427	No alias	purine nucleotide binding protein	0.02	OF
EDN91508	No alias	DNA replication factor RFC1, C-terminal	0.04	OF
EED80531	No alias	BRCT domain	0.02	OF
EGR52246	No alias	BRCT domain	0.09	OF
ESU05491	No alias	replication factor C subunit 1	0.06	OF
KHC81620	No alias	replication factor C subunit 1;ATPase family associated...	0.11	OF
MGG_03204T0	No alias	Replication factor C subunit 1...	0.04	OF
SPBC23E6.07c.1	No alias	DNA replication factor C complex subunit Rfc1...	0.04	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003689	DNA clamp loader activity	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005663	DNA replication factor C complex	IEA	Interproscan
BP	GO:0006260	DNA replication	IEA	Interproscan
MF	GO:0008094	DNA-dependent ATPase activity	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
MF	GO:0033170	protein-DNA loading ATPase activity	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR013725	DNA_replication_fac_RFC1_C	621	776
IPR003959	ATPase_AAA_core	350	449
IPR001357	BRCT_dom	154	230

External Links

No external refs found!

YOR217W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation