YOL151W

Description : 3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase; stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway; restores resistance to glycolaldehyde by coupling reduction of glycolaldehyde to ethylene glycol and oxidation of NADPH to NADP+; protein abundance increases in response to DNA replication stress; methylglyoxal reductase (NADPH-dependent) is also known as D-lactaldehyde dehydrogenase [Source:SGD;Acc:S000005511]

Gene families : OG_03_0000047 (OF) Phylogenetic Tree(s): OG0000047_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YOL151W
Cluster	HCCA: Cluster_19

Target	Alias	Description	ECC score	Gene Family Method
AFR95638	No alias	D-lactaldehyde dehydrogenase;NAD dependent...	0.03	OF
AFR96623	No alias	oxidoreductase;3-beta hydroxysteroid...	0.04	OF
AOA68281	No alias	NAD-dependent epimerase/dehydratase	0.08	OF
AOA68895	No alias	NAD-dependent epimerase/dehydratase	0.11	OF
AOA69938	No alias	NAD-dependent epimerase/dehydratase	0.03	OF
CAG77997	No alias	NAD-dependent epimerase/dehydratase	0.04	OF
CAG78658	No alias	NAD-dependent epimerase/dehydratase	0.03	OF
CAG80702	No alias	NAD-dependent epimerase/dehydratase	0.07	OF
CAK38896	No alias	NAD dependent epimerase/dehydratase family	0.03	OF
CAK39886	No alias	NAD dependent epimerase/dehydratase family	0.03	OF
CAK43535	No alias	NAD dependent epimerase/dehydratase family	0.06	OF
CAK46043	No alias	NAD dependent epimerase/dehydratase family	0.05	OF
CAK48422	No alias	NAD dependent epimerase/dehydratase family	0.02	OF
CBF88830	No alias	3-beta hydroxysteroid dehydrogenase/isomerase family protein	0.05	OF
EAL93323	No alias	ketoreductase	0.03	OF
EAL94083	No alias	3-beta hydroxysteroid dehydrogenase/isomerase, putative	0.03	OF
EAU87173	No alias	NAD-dependent epimerase/dehydratase	0.02	OF
EDN91112	No alias	NAD-dependent epimerase/dehydratase	0.02	OF
EED82210	No alias	NAD-dependent epimerase/dehydratase	0.02	OF
EED86030	No alias	NAD-dependent epimerase/dehydratase	0.08	OF
EGR44747	No alias	NAD-dependent epimerase/dehydratase	0.02	OF
EGR44946	No alias	NAD-dependent epimerase/dehydratase	0.03	OF
EGR46410	No alias	NAD-dependent epimerase/dehydratase	0.04	OF
EGR49588	No alias	NAD-dependent epimerase/dehydratase	0.02	OF
EGR51087	No alias	NAD-dependent epimerase/dehydratase	0.05	OF
EJF56274	No alias	NAD dependent epimerase/dehydratase family	0.02	OF
EJF59004	No alias	NAD dependent epimerase/dehydratase family	0.07	OF
EJF59005	No alias	NAD dependent epimerase/dehydratase family	0.05	OF
EJF59014	No alias	NAD dependent epimerase/dehydratase family	0.03	OF
EJF59015	No alias	NAD dependent epimerase/dehydratase family	0.12	OF
EJF59795	No alias	NAD dependent epimerase/dehydratase family	0.09	OF
EJF61546	No alias	NAD dependent epimerase/dehydratase family	0.05	OF
ESU06800	No alias	NAD-dependent epimerase/dehydratase	0.03	OF
ESU14981	No alias	NAD-dependent epimerase/dehydratase	0.05	OF
ESU17450	No alias	NAD-dependent epimerase/dehydratase	0.02	OF
KHC71157	No alias	hypothetical protein;NAD dependent epimerase/dehydratase family	0.02	OF
KHC75185	No alias	hypothetical protein;NAD dependent epimerase/dehydratase family	0.15	OF
KHC81706	No alias	hypothetical protein;NAD dependent epimerase/dehydratase family	0.08	OF
SPAC513.07.1	No alias	flavonol reductase/cinnamoyl-CoA reductase family...	0.06	OF
SPBC1773.04.1	No alias	methylglyoxyl reductase (NADPH-dependent) (predicted)...	0.04	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity	IEA	Interproscan
BP	GO:0006629	lipid metabolic process	None	Extended
BP	GO:0006694	steroid biosynthetic process	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008202	steroid metabolic process	None	Extended
BP	GO:0008610	lipid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
MF	GO:0016229	steroid dehydrogenase activity	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	None	Extended
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA	Interproscan
MF	GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0055114	oxidation-reduction process	IEA	Interproscan
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR002225	3Beta_OHSteriod_DH/Estase	5	257

External Links

No external refs found!

YOL151W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation