YNL298W

Description : Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]

Gene families : OG_03_0000302 (OF) Phylogenetic Tree(s): OG0000302_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YNL298W
Cluster	HCCA: Cluster_18

Target	Alias	Description	ECC score	Gene Family Method
CAK40664	No alias	P21-Rho-binding domain	0.02	OF
CAK43074	No alias	Pleckstrin homology domain	0.02	OF
CBF77917	No alias	conserved hypothetical protein similar to p21-activated kinase	0.03	OF
EAA28056	No alias	CRIB domain	0.02	OF
EAL92004	No alias	protein kinase (Chm1), putative	0.03	OF
EAU87328	No alias	STE/STE20/PAKA protein kinase	0.04	OF
EAU90456	No alias	STE/STE20/PAKA protein kinase	0.02	OF
EDN91234	No alias	CRIB domain	0.02	OF
EDN99594	No alias	Protein kinase domain	0.02	OF
EGR51173	No alias	Protein kinase domain	0.05	OF
EGR52789	No alias	Protein kinase domain	0.05	OF
ESU16087	No alias	serine/threonine-protein kinase MST20	0.03	OF
KHC75134	No alias	serine/threonine-protein kinase CST20;Protein kinase...	0.03	OF
KHC83765	No alias	serine/threonine-protein kinase CLA4;Protein kinase...	0.03	OF
POW07014	No alias	CRIB domain;Protein kinase domain;Haspin like kinase domain	0.03	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004672	protein kinase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006468	protein phosphorylation	IEA	Interproscan
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016301	kinase activity	None	Extended
BP	GO:0016310	phosphorylation	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0036211	protein modification process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR000095	CRIB_dom	184	241
IPR001849	PH_domain	63	175
IPR000719	Prot_kinase_dom	588	825

External Links

No external refs found!

YNL298W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation