Description : Ubiquitin-specific protease, deubiquitinates Ub-protein moieties; interacts with proteins that function in rRNA production and ribosome biogenesis via its intrinsically disordered regions; stabilizes Rpa190p by deubiquitination; controls PCNA deubiquitylation; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p, possibly other transporters; localized to the nucleolus; null mutant phenotypes are functionally complemented by human USP36 [Source:SGD;Acc:S000005130]
Gene families : OG_03_0000777 (OF) Phylogenetic Tree(s): OG0000777_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YNL186W | |
Cluster | HCCA: Cluster_63 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AOA65875 | No alias | Peptidase C19, ubiquitin carboxyl-terminal hydrolase | 0.05 | OF | |
AOA66856 | No alias | Peptidase C19, ubiquitin carboxyl-terminal hydrolase | 0.05 | OF | |
CAG81423 | No alias | Peptidase C19, ubiquitin carboxyl-terminal hydrolase | 0.06 | OF | |
EDN96929 | No alias | Peptidase C19, ubiquitin carboxyl-terminal hydrolase | 0.12 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0016579 | protein deubiquitination | IEA | Interproscan |
MF | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR001394 | Peptidase_C19_UCH | 363 | 730 |
No external refs found! |