YNL186W


Description : Ubiquitin-specific protease, deubiquitinates Ub-protein moieties; interacts with proteins that function in rRNA production and ribosome biogenesis via its intrinsically disordered regions; stabilizes Rpa190p by deubiquitination; controls PCNA deubiquitylation; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p, possibly other transporters; localized to the nucleolus; null mutant phenotypes are functionally complemented by human USP36 [Source:SGD;Acc:S000005130]


Gene families : OG_03_0000777 (OF) Phylogenetic Tree(s): OG0000777_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YNL186W
Cluster HCCA: Cluster_63

Target Alias Description ECC score Gene Family Method Actions
AOA65875 No alias Peptidase C19, ubiquitin carboxyl-terminal hydrolase 0.05 OF
AOA66856 No alias Peptidase C19, ubiquitin carboxyl-terminal hydrolase 0.05 OF
CAG81423 No alias Peptidase C19, ubiquitin carboxyl-terminal hydrolase 0.06 OF
EDN96929 No alias Peptidase C19, ubiquitin carboxyl-terminal hydrolase 0.12 OF

Type GO Term Name Evidence Source
BP GO:0016579 protein deubiquitination IEA Interproscan
MF GO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR001394 Peptidase_C19_UCH 363 730
No external refs found!