YNL172W

Description : Largest subunit of the Anaphase-Promoting Complex/Cyclosome; APC/C is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; component of the platform domain of the APC/C, based on structural analysis; localizes to nuclear foci that become diffuse upon DNA replication stress [Source:SGD;Acc:S000005116]

Gene families : OG_03_0003513 (OF) Phylogenetic Tree(s): OG0003513_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YNL172W
Cluster	HCCA: Cluster_3

Target	Alias	Description	ECC score	Gene Family Method
AOA66904	No alias	Anaphase-promoting complex subunit 1	0.03	OF
CAG81106	No alias	Anaphase-promoting complex subunit 1	0.02	OF
CAK40864	No alias	Anaphase-promoting complex subunit 1	0.05	OF
KHC82851	No alias	anaphase-promoting complex subunit 1;Anaphase-promoting...	0.04	OF

Type	GO Term	Name	Evidence	Source
CC	GO:0000151	ubiquitin ligase complex	None	Extended
CC	GO:0000152	nuclear ubiquitin ligase complex	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005680	anaphase-promoting complex	IEA	Interproscan
CC	GO:0031461	cullin-RING ubiquitin ligase complex	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
CC	GO:1902494	catalytic complex	None	Extended
CC	GO:1990234	transferase complex	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR024990	Apc1	87	266

External Links

No external refs found!

YNL172W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation