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  5. YMR247C

YMR247C


Description : RING domain E3 ubiquitin ligase; involved in ubiquitin-mediated degradation of non-stop proteins and translationally stalled ER membrane proteins; component of ribosome-bound RQC (ribosome quality control) complex; degrades products of mRNAs lacking a termination codon regardless of a poly(A) tail; functional connections to chromatin modification; homolog of mouse Listerin, mutations in which reported to cause neurodegeneration [Source:SGD;Acc:S000004861]


Gene families : OG_03_0002861 (OF) Phylogenetic Tree(s): OG0002861_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YMR247C
Cluster HCCA: Cluster_12

Target Alias Description ECC score Gene Family Method Actions
AOA65932 No alias Zinc finger, RING-type 0.07 OF
CAG80051 No alias Zinc finger, RING-type 0.04 OF
CBF88903 No alias RING zinc finger protein, putative 0.08 OF
EAL90724 No alias RING zinc finger protein, putative 0.02 OF
EGR44789 No alias Zinc finger, RING-type 0.02 OF
KHC73538 No alias hypothetical protein 0.1 OF
KHC73539 No alias hypothetical protein;Ring finger domain 0.12 OF
MGG_10526T0 No alias Putative uncharacterized protein... 0.02 OF
POW11902 No alias hypothetical protein 0.03 OF
SPBC21D10.09c.1 No alias RQC complex ubiquitin-protein ligase E3 Rkr1 (predicted)... 0.15 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR001841 Znf_RING 1507 1555
No external refs found!