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Expression profile for YMR247C (YMR247C)

Description : RING domain E3 ubiquitin ligase; involved in ubiquitin-mediated degradation of non-stop proteins and translationally stalled ER membrane proteins; component of ribosome-bound RQC (ribosome quality control) complex; degrades products of mRNAs lacking a termination codon regardless of a poly(A) tail; functional connections to chromatin modification; homolog of mouse Listerin, mutations in which reported to cause neurodegeneration [Source:SGD;Acc:S000004861]

Sample enrichment: gal, 2h + hu 200 mm,WT (SPM: 0.28, entropy: 3.85, tau: 0.6)
Perturbation specificity: Gal (SPM: 0.5, entropy: 2.69, tau: 0.54)

All conditions


Perturbation specificity

Note: SPM calculations for this profile are done using the maximum value.