Description : Dehydrogenase involved in ubiquinone and sphingolipid metabolism; oxidizes 4-hydroxybenzaldehyde into 4-hydroxybenzoic acid in ubiquinone biosynthesis; converts hexadecenal to hexadecenoic acid in sphingosine 1-phosphate breakdown pathway; located in the mitochondrial outer membrane and also in lipid particles; human homolog ALDH3A2, a fatty aldehyde dehydrogenase (FALDH) mutated in neurocutaneous disorder Sjogren-Larsson syndrome, can complement yeast hfd1 mutant [Source:SGD;Acc:S000004716]
Gene families : OG_03_0000454 (OF) Phylogenetic Tree(s): OG0000454_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YMR110C | |
| Cluster | HCCA: Cluster_26 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| AOA66353 | No alias | Aldehyde dehydrogenase domain | 0.11 | OF | |
| CAG84111 | No alias | Aldehyde dehydrogenase domain | 0.03 | OF | |
| CAK43976 | No alias | Aldehyde dehydrogenase family | 0.03 | OF | |
| CBF81490 | No alias | aldehyde dehydrogenase, putative | 0.03 | OF | |
| EAL89443 | No alias | aldehyde dehydrogenase, putative | 0.02 | OF | |
| EGR53121 | No alias | Aldehyde dehydrogenase domain | 0.03 | OF | |
| ESA42262 | No alias | Aldehyde dehydrogenase domain | 0.02 | OF | |
| POV99278 | No alias | Aldehyde dehydrogenase domain | 0.02 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0016491 | oxidoreductase activity | IEA | Interproscan |
| BP | GO:0055114 | oxidation-reduction process | IEA | Interproscan |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR015590 | Aldehyde_DH_dom | 43 | 463 |
| No external refs found! |