YMR038C


Description : Copper chaperone for superoxide dismutase Sod1p; involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within N-terminus is involved in insertion of copper into Sod1p under conditions of copper deprivation; required for regulation of yeast copper genes in response to DNA-damaging agents; protein abundance increases in response to DNA replication stress; human homolog CCS can complement yeast ccs1 null mutant [Source:SGD;Acc:S000004641]


Gene families : OG_03_0003563 (OF) Phylogenetic Tree(s): OG0003563_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YMR038C
Cluster HCCA: Cluster_19

Target Alias Description ECC score Gene Family Method Actions
CBF70298 No alias superoxide dismutase copper chaperone Lys7, putative 0.02 OF
EAA33876 No alias Superoxide dismutase, copper/zinc binding domain 0.08 OF
EAL93265 No alias superoxide dismutase copper chaperone Lys7, putative 0.05 OF
EGR50173 No alias Heavy metal-associated domain, HMA 0.02 OF
KHC83479 No alias superoxide dismutase 1 copper... 0.07 OF
MGG_05281T0 No alias Superoxide dismutase copper chaperone Lys7, variant... 0.04 OF
MGG_05281T1 No alias Superoxide dismutase copper chaperone Lys7, variant... 0.02 OF

Type GO Term Name Evidence Source
BP GO:0006801 superoxide metabolic process IEA Interproscan
BP GO:0030001 metal ion transport IEA Interproscan
MF GO:0046872 metal ion binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR006121 HMA_dom 11 67
IPR001424 SOD_Cu_Zn_dom 97 194
No external refs found!