Description : Copper chaperone for superoxide dismutase Sod1p; involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within N-terminus is involved in insertion of copper into Sod1p under conditions of copper deprivation; required for regulation of yeast copper genes in response to DNA-damaging agents; protein abundance increases in response to DNA replication stress; human homolog CCS can complement yeast ccs1 null mutant [Source:SGD;Acc:S000004641]
Gene families : OG_03_0003563 (OF) Phylogenetic Tree(s): OG0003563_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YMR038C | |
Cluster | HCCA: Cluster_19 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
CBF70298 | No alias | superoxide dismutase copper chaperone Lys7, putative | 0.02 | OF | |
EAA33876 | No alias | Superoxide dismutase, copper/zinc binding domain | 0.08 | OF | |
EAL93265 | No alias | superoxide dismutase copper chaperone Lys7, putative | 0.05 | OF | |
EGR50173 | No alias | Heavy metal-associated domain, HMA | 0.02 | OF | |
KHC83479 | No alias | superoxide dismutase 1 copper... | 0.07 | OF | |
MGG_05281T0 | No alias | Superoxide dismutase copper chaperone Lys7, variant... | 0.04 | OF | |
MGG_05281T1 | No alias | Superoxide dismutase copper chaperone Lys7, variant... | 0.02 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0006801 | superoxide metabolic process | IEA | Interproscan |
BP | GO:0030001 | metal ion transport | IEA | Interproscan |
MF | GO:0046872 | metal ion binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |