YML126C

Description : 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase; catalyzes the formation of HMG-CoA from acetyl-CoA and acetoacetyl-CoA; involved in the second step in mevalonate biosynthesis [Source:SGD;Acc:S000004595]

Gene families : OG_03_0001070 (OF) Phylogenetic Tree(s): OG0001070_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YML126C
Cluster	HCCA: Cluster_17

Target	Alias	Description	ECC score	Gene Family Method
AFR93795	No alias	hydroxymethylglutaryl-CoA...	0.17	OF
AFR96532	No alias	hydroxymethylglutaryl-CoA...	0.12	OF
AOA67272	No alias	Hydroxymethylglutaryl-coenzyme A synthase, N-terminal	0.03	OF
CAG78865	No alias	Hydroxymethylglutaryl-coenzyme A synthase, N-terminal	0.12	OF
CAK48176	No alias	Hydroxymethylglutaryl-coenzyme A synthase C terminal	0.02	OF
CAL00631	No alias	Hydroxymethylglutaryl-coenzyme A synthase C terminal	0.02	OF
CBF76472	No alias	hydroxymethylglutaryl-CoA synthase, expressed	0.07	OF
EAA28325	No alias	Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain	0.04	OF
EAU90443	No alias	hydroxymethylglutaryl-CoA synthase	0.19	OF
EDO00563	No alias	Hydroxymethylglutaryl-coenzyme A synthase, N-terminal	0.06	OF
EGR51279	No alias	Hydroxymethylglutaryl-coenzyme A synthase, N-terminal	0.12	OF
EJF57229	No alias	Hydroxymethylglutaryl-coenzyme A synthase N terminal	0.02	OF
ESU15814	No alias	hydroxymethylglutaryl-CoA synthase	0.14	OF
KHC69662	No alias	hydroxymethylglutaryl-CoA...	0.12	OF
MGG_01026T0	No alias	Hydroxymethylglutaryl-CoA synthase...	0.02	OF
SPAC4F8.14c.1	No alias	3-hydroxy-3-methylglutaryl-CoA synthase...	0.04	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004421	hydroxymethylglutaryl-CoA synthase activity	IEA	Interproscan
BP	GO:0006629	lipid metabolic process	None	Extended
BP	GO:0006720	isoprenoid metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008299	isoprenoid biosynthetic process	IEA	Interproscan
BP	GO:0008610	lipid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016746	transferase activity, transferring acyl groups	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044255	cellular lipid metabolic process	None	Extended
MF	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR013746	HMG_CoA_synt_C_dom	217	490
IPR013528	HMG_CoA_synth_N	45	216

External Links

No external refs found!

YML126C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation