Description : Major orotate phosphoribosyltransferase (OPRTase) isozyme; catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; URA5 has a paralog, URA10, that arose from the whole genome duplication [Source:SGD;Acc:S000004574]
Gene families : OG_03_0002706 (OF) Phylogenetic Tree(s): OG0002706_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YML106W | |
Cluster | HCCA: Cluster_69 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR96423 | No alias | orotate phosphoribosyltransferase;Phosphoribosyl... | 0.07 | OF | |
CAG78523 | No alias | Phosphoribosyltransferase domain | 0.06 | OF | |
CBF70640 | No alias | orotate phosphoribosyltransferase | 0.03 | OF | |
EAA32825 | No alias | Phosphoribosyltransferase domain | 0.04 | OF | |
EDN96422 | No alias | Phosphoribosyltransferase domain | 0.18 | OF | |
EGR51642 | No alias | Phosphoribosyltransferase domain | 0.09 | OF | |
ESU12223 | No alias | orotate phosphoribosyltransferase | 0.03 | OF | |
KHC71141 | No alias | orotate phosphoribosyltransferase;Phosphoribosyl... | 0.02 | OF | |
MGG_07135T0 | No alias | Orotate phosphoribosyltransferase... | 0.13 | OF | |
POV95142 | No alias | Phosphoribosyltransferase domain | 0.02 | OF | |
SPBC725.15.1 | No alias | orotate phosphoribosyltransferase Ura5... | 0.05 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0009116 | nucleoside metabolic process | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR000836 | PRibTrfase_dom | 50 | 174 |
No external refs found! |