YML061C


Description : DNA helicase, potent G-quadruplex DNA binder/unwinder; possesses strand annealing activity; promotes DNA synthesis during break-induced replication; important for crossover recombination; translation from different start sites produces mitochondrial and nuclear forms; nuclear form is a catalytic inhibitor of telomerase; mitochondrial form involved in DNA repair and recombination; mutations affect Zn, Fe homeostasis; regulated by Rad53p-dependent phosphorylation in rho0 cells [Source:SGD;Acc:S000004526]


Gene families : OG_03_0000319 (OF) Phylogenetic Tree(s): OG0000319_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YML061C
Cluster HCCA: Cluster_37

Target Alias Description ECC score Gene Family Method Actions
AOA67010 No alias DNA helicase Pif1-like 0.04 OF
CAG80813 No alias DNA helicase Pif1-like 0.07 OF
CAG83665 No alias DNA helicase Pif1-like 0.03 OF
CAG83912 No alias DNA helicase Pif1-like 0.1 OF
CBF71681 No alias helicase 0.06 OF
EAA27456 No alias DNA helicase Pif1-like 0.07 OF
EAL91279 No alias mitochondrial DNA helicase (Pif1), putative 0.09 OF
EAU90478 No alias DNA repair and recombination protein pif1 0.04 OF
EDO00866 No alias Zinc finger, CCHC-type 0.03 OF
EFI28655 No alias DNA repair and recombination protein pif1 0.02 OF
KHC70591 No alias ATP-dependent DNA helicase PIF1;PIF1-like helicase 0.05 OF
MGG_05212T0 No alias Putative uncharacterized protein... 0.05 OF
POW07787 No alias DNA helicase Pif1-like;Ribonuclease H1, N-terminal 0.03 OF
POW13316 No alias DNA helicase Pif1-like 0.04 OF

Type GO Term Name Evidence Source
BP GO:0000723 telomere maintenance IEA Interproscan
MF GO:0003678 DNA helicase activity IEA Interproscan
BP GO:0006281 DNA repair IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR010285 DNA_helicase_pif1-like 459 542
IPR010285 DNA_helicase_pif1-like 236 443
No external refs found!