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  5. YLR442C

YLR442C


Description : Silencing protein; interacts with Sir2p, Sir4p, and histone H3/H4 tails to establish transcriptionally silent chromatin; required for spreading of silenced chromatin; recruited to chromatin through interaction with Rap1p; C-terminus assumes variant winged helix-turn-helix (wH) fold that mediates homodimerization, which is critical for holo-SIR complex loading; required for telomere hypercluster formation in quiescent yeast cells; has paralog ORC1 from whole genome duplication [Source:SGD;Acc:S000004434]


Gene families : OG_03_0001284 (OF) Phylogenetic Tree(s): OG0001284_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YLR442C
Cluster HCCA: Cluster_63

Target Alias Description ECC score Gene Family Method Actions
AOA70326 No alias AAA lid domain 0.03 OF
CAG80833 No alias ATPase, AAA-type, core 0.04 OF
CAK45318 No alias ATPase family associated with various cellular activities (AAA) 0.02 OF
EAU91735 No alias replication control protein 1 0.02 OF
EGR50790 No alias ATPase, AAA-type, core 0.02 OF
KHC83088 No alias origin recognition complex subunit 1;AAA lid... 0.12 OF
MGG_05615T0 No alias Origin recognition complex subunit 1... 0.02 OF

Type GO Term Name Evidence Source
MF GO:0003682 chromatin binding IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR001025 BAH_dom 50 187
IPR041083 AAA_lid_10 736 833
No external refs found!