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Expression profile for YLR442C (YLR442C)

Description : Silencing protein; interacts with Sir2p, Sir4p, and histone H3/H4 tails to establish transcriptionally silent chromatin; required for spreading of silenced chromatin; recruited to chromatin through interaction with Rap1p; C-terminus assumes variant winged helix-turn-helix (wH) fold that mediates homodimerization, which is critical for holo-SIR complex loading; required for telomere hypercluster formation in quiescent yeast cells; has paralog ORC1 from whole genome duplication [Source:SGD;Acc:S000004434]

Sample enrichment: synthetic complete med,20C,WT (SPM: 0.26, entropy: 3.71, tau: 0.52)
Perturbation specificity: YPD (SPM: 0.45, entropy: 2.69, tau: 0.43)